7 Result(s)
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Article
Open AccessAdaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system
Vancomycin resistant enterococci (VRE) are a leading cause of ICU-acquired bloodstream infections in Europe. The bacterial load in enteral colonization may be associated with a higher probability of transmissi...
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Open AccessProspective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases
Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic with significant mortality. Accurate information on the specific circumst...
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Article
Open AccessComparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza
While several studies have described the clinical course of patients with coronavirus disease 2019 (COVID-19), direct comparisons with patients with seasonal influenza are scarce. We compared 166 patients with...
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Article
Open AccessAntibiotic sensitivity in correlation to the origin of secondary peritonitis: a single center analysis
Despite improvements in diagnosis, intensive-care medicine and surgical technique, the mortality of patients with secondary peritonitis is still high. Early and aggressive empiric antibiotic treatment has stro...
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Article
Open AccessDAMIAN: an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples
We describe DAMIAN, an open source bioinformatics tool designed for the identification of pathogenic microorganisms in diagnostic samples. By using authentic clinical samples and comparing our results to those...
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Article
Open AccessBoth interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
Co-infection with hepatitis B (HBV) and D virus (HDV) is associated with the most severe course of liver disease. Interferon represents the only treatment currently approved. However, knowledge about the impac...
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Article
Open AccessAttenuated viral hepatitis in Trem1−/− mice is associated with reduced inflammatory activity of neutrophils
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in live...
