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  1. Article

    Open Access

    RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma

    RORγt is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a pharmacological target for severe asthma.

    David Lamb, Dorothy De Sousa, Karsten Quast, Katrin Fundel-Clemens… in Respiratory Research (2021)

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  2. Article

    Open Access

    Automatization and improvement of μCT analysis for murine lung disease models using a deep learning approach

    One of the main diagnostic tools for lung diseases in humans is computed tomography (CT). A miniaturized version, micro-CT (μCT) is utilized to examine small rodents including mice. However, fully automated th...

    Gerald Birk, Marc Kästle, Cornelia Tilp, Birgit Stierstorfer… in Respiratory Research (2020)

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