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  1. Article

    Open Access

    Decreased microbiome diversity in the HIV small airway epithelium

    Persons living with human immunodeficiency virus (PLWH) face an increased burden of chronic obstructive pulmonary disease (COPD). Repeated pulmonary infections, antibiotic exposures, and immunosuppression may ...

    Stella Xu, Amy Tsai, Marc A. Sze, Emily A. Vucic in Respiratory Research (2018)

  2. Article

    Open Access

    Normalization of the microbiota in patients after treatment for colonic lesions

    Colorectal cancer is a worldwide health problem. Despite growing evidence that members of the gut microbiota can drive tumorigenesis, little is known about what happens to it after treatment for an adenoma or ...

    Marc A. Sze, Nielson T. Baxter, Mack T. Ruffin IV, Mary A. M. Rogers in Microbiome (2017)

  3. Article

    Open Access

    The cellular and molecular determinants of emphysematous destruction in COPD

    The introduction of microCT has made it possible to show that the terminal bronchioles are narrowed and destroyed before the onset of emphysematous destruction in COPD. This report extends those observations t...

    Masaru Suzuki, Marc A. Sze, Joshua D. Campbell, John F. Brothers II in Scientific Reports (2017)

  4. Article

    Open Access

    Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori

    Helicobacter pylori (HP) infection is associated with reduced lung function and systemic inflammation in chronic obstructive pulmonary disease (COPD) patients. Azithromycin (AZ) is act...

    Seung Won Ra, Marc A. Sze, Eun Chong Lee, Sheena Tam, Yeni Oh in Respiratory Research (2017)

  5. Article

    Open Access

    The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus

    Chronic Obstructive Pulmonary Disease (COPD) is an important comorbidity in patients living with human immunodeficiency virus (HIV). Previous bacterial microbiome studies have shown increased abundance of spec...

    Marc A. Sze, Stella Xu, Janice M. Leung, Emily A. Vucic in BMC Pulmonary Medicine (2016)