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Article
New photobiomodulation device for prevention and cure of radiotherapy-induced oral mucositis and dermatitis: results of the prospective Safe PBM study
The study aims to assess the feasibility, safety, and tolerability of CareMin650, a new photobiomodulation device, in patients treated by radiotherapy (RT) and to collect preliminary data on efficacy for preve...
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Article
Preliminary experience of whole-brain radiation therapy (WBRT) in breast cancer patients with brain metastases previously treated with bevacizumab-based chemotherapy
We report our experience of bevacizumab-based chemotherapy (BBCT) followed by whole-brain radiation therapy (WBRT) for breast cancer (BC) patients (pts) with inoperable brain metastases (BM) or who refused sur...
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Article
Open AccessTargeting poly(ADP-ribose) polymerase activity for cancer therapy
Poly(ADP-ribosyl)ation is a ubiquitous protein modification found in mammalian cells that modulates many cellular responses, including DNA repair. The poly(ADP-ribose) polymerase (PARP) family catalyze the for...
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Article
Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis
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Article
Open AccessAnalysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis
We present a computational method, TuMult, for reconstructing the sequence of copy number changes driving carcinogenesis, based on the analysis of several tumor samples from the same patient. We demonstrate th...
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Article
Open AccessTumor aromatase expression as a prognostic factor for local control in young breast cancer patients after breast-conserving treatment
We sought to determine whether the levels of expression of 17 candidate genes were associated with locoregional control after breast-conserving treatments of early-stage breast cancers in young, premenopausal ...