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Article
Open AccessIncreased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham-controlled trial
SNT is a high-dose accelerated intermittent theta-burst stimulation (iTBS) protocol coupled with functional-connectivity-guided targeting that is an efficacious and rapid-acting therapy for treatment-resistant...
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Article
Open AccessBrain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior relationship has not been systematically studied at a brain-w...
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Article
Open AccessNetwork effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial
Here, we investigated the brain functional connectivity (FC) changes following a novel accelerated theta burst stimulation protocol known as Stanford Neuromodulation Therapy (SNT) which demonstrated significan...
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Chapter
NeuroDesign: Greater than the Sum of Its Parts
This chapter outlines the recent developments, such as neuroscience on design, design neurocognition, and NeuroDesign, in the intersection of neuroscience and design. This intersection of diverse disciplines, ...
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Article
Open AccessPrecision dynamical map** using topological data analysis reveals a hub-like transition state at rest
In the absence of external stimuli, neural activity continuously evolves from one configuration to another. Whether these transitions or explorations follow some underlying arrangement or lack a predictable or...
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Article
Altered canonical and striatal-frontal resting state functional connectivity in children with pathogenic variants in the Ras/mitogen-activated protein kinase pathway
Mounting evidence supports the role of the Ras/mitogen-activated protein kinase (Ras/MAPK) pathway in neurodevelopmental disorders. Here, the authors used a genetics-first approach to examine how Ras/MAPK path...
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Article
Open AccessThalamic and prefrontal GABA concentrations but not GABAA receptor densities are altered in high-functioning adults with autism spectrum disorder
The gamma aminobutyric acid (GABA) neurotransmission system has been implicated in autism spectrum disorder (ASD). Molecular neuroimaging studies incorporating simultaneous acquisitions of GABA concentrations ...
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Article
Open AccessThalamocortical connectivity is associated with autism symptoms in high-functioning adults with autism and typically develo** adults
Alterations in sensorimotor functions are common in individuals with autism spectrum disorder (ASD). Such aberrations suggest the involvement of the thalamus due to its key role in modulating sensorimotor sign...
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NeuroDesign: From Neuroscience Research to Design Thinking Practice
There is an increasing use of neuroscience research methods to understand the neural basis of design activity. The use of Neuroscience research tools such as fMRI, EEG and fNIRS presents a new and insightful a...
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Examining the Neurocognitive Basis of Applied Creativity in Entrepreneurs and Managers
Creativity and innovation lie at the heart of design thinking. Understanding how creativity is manifested in the brain is perhaps one of the most significant challenges of the twenty-first century. However, mo...
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Mining the Role of Design Reflection and Associated Brain Dynamics in Creativity
Reflection—the activity of reasoning through an action that has occurred—has been shown to be of importance to the development of design expertise. Although design reflection has been widely studied previously...
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Article
Open AccessTowards a new approach to reveal dynamical organization of the brain using topological data analysis
Little is known about how our brains dynamically adapt for efficient functioning. Most previous work has focused on analyzing changes in co-fluctuations between a set of brain regions over several temporal seg...
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Creativity in the Twenty-first Century: The Added Benefit of Training and Cooperation
Creativity is an important construct driving society and innovation forward. Many organizations have adopted team-based work in order to increase innovation and creativity under the assumption that groups of p...
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Article
Open AccessCorrection: Corrigendum: Sex differences in neural and behavioral signatures of cooperation revealed by fNIRS hyperscanning
Scientific Reports 6: Article number: 26492; published online: 08 June 2016; updated: 19 August 2016. In this Article, the authors mistakenly used the abbreviation “r” instead of “b” to refer to the beta coeff...
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Open AccessSex differences in neural and behavioral signatures of cooperation revealed by fNIRS hyperscanning
Researchers from multiple fields have sought to understand how sex moderates human social behavior. While over 50 years of research has revealed differences in cooperation behavior of males and females, the un...
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Develo** Novel Neuroimaging Paradigm to Assess Neural Correlates of Improvisation and Creative Thinking Using fMRI
The ability to produce novel yet appropriate (or useful) outcomes is broadly defined as creativity. Given the cultural significance of creativity, researchers have been attempting to uncover brain mechanisms u...
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Designing a Creativity Assessment Tool for the Twenty-First Century: Preliminary Results and Insights from Develo** a Design-Thinking Based Assessment of Creative Capacity
In order to assess a person’s creative capacity in real-world situations, we propose a novel Design Thinking Creativity Test (DTCT). The DTCT is based on the design thinking principles and can serve as an asse...
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Article
Open AccessPictionary-based fMRI paradigm to study the neural correlates of spontaneous improvisation and figural creativity
A novel game-like and creativity-conducive fMRI paradigm is developed to assess the neural correlates of spontaneous improvisation and figural creativity in healthy adults. Participants were engaged in the wor...
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Chapter
Develo** Novel Methods to Assess Long-Term Sustainability of Creative Capacity Building and Applied Creativity
Creativity, the ability to create novel and useful outcomes, has been widely recognized as an essential skill for both entrepreneurial and every-day success. Given the vital import of creativity in our everyda...
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Impact and Sustainability of Creative Capacity Building: The Cognitive, Behavioral, and Neural Correlates of Increasing Creative Capacity
The impact and sustainability of creative capacity building over time is examined using both neural and psychological approaches. Our research proposes a unique experimental design to test whether creativity c...
