7 Result(s)
within
Manish Sadarangani
Pediatrics
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Article
Paediatric inflammatory multisystem syndrome in Canada: population-based surveillance and role of SARS-CoV-2 linkage
Paediatric inflammatory multisystem syndrome (PIMS) is a rare condition temporally associated with SARS-CoV-2 infection. Using national surveillance data, we compare presenting features and outcomes among chil...
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Article
Infants hospitalized for acute COVID-19: disease severity in a multicenter cohort study
Age is the most important determinant of COVID-19 severity. Infectious disease severity by age is typically J-shaped, with infants and the elderly carrying a high burden of disease. We report on the comparativ...
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Article
Open AccessChild transmission of SARS-CoV-2: a systematic review and meta-analysis
Understanding of the role of children in COVID-19 transmission has significant implications for school and childcare policies, as well as appropriate targeting of vaccine campaigns. The objective of this syste...
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Chapter
Meningococcal Vaccines
Neisseria meningitidis (the meningococcus) is a Gram-negative diplococcus, which causes meningitis and septicaemia with a high case fatality rate and many survivors suffering from long-term neurological and non-n...
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Article
Open AccessStudy protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT: a multicentre, randomised controlled 2 × 2 factorial trial to investigate techniques to increase lumbar puncture success
The neonatal period carries the highest risk of bacterial meningitis (~ 1 in 5000 births), bearing high mortality (~ 10%) and morbidity (20–50%) rates. Lumbar puncture (LP) remains essential to the diagnosis o...
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Article
Open AccessThe prevalence and clinical characteristics of pertussis-associated pneumonia among infants in Botswana
There are scant data on the prevalence and clinical course of pertussis disease among infants with pneumonia in low- and middle-income countries. While pertussis vaccination coverage is high (≥90%) among infan...
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Chapter
Meningococcal Vaccines
Meningococcal disease was first described in Europe as a characteristic outbreak in Geneva in 1805. Neisseria meningitidis (the meningococcus) is a Gram-negative diplococcus, divided into capsular groups determin...
