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Article
Open AccessThe M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus
Cell rounding is a hallmark of the cytopathic effect induced by cytomegaloviruses. By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutant was identified that did not elicit cell roun...
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Article
Conditional and reversible disruption of essential herpesvirus proteins
A system for inducible protein degradation, originally developed for mammalian cells, is applied to essential viral proteins and will allow functional studies in a wide range of viruses.