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Article
The circadian clock as a potential biomarker and therapeutic target in pancreatic cancer
Pancreatic cancer (PC) has a very high mortality rate globally. Despite ongoing efforts, its prognosis has not improved significantly over the last two decades. Thus, further approaches for optimizing treatmen...
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Article
Therapeutic potency of A1 adenosine receptor antagonists in the treatment of cardiovascular diseases, current status and perspectives
Cardiomyocytes form, transport, and metabolize the omnipresent metabolite adenosine. Depending upon the adenosine concentrations and the pharmacological properties of receptor subtypes, adenosine exerts (patho...
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Article
Open AccessMicrobiome as a biomarker and therapeutic target in pancreatic cancer
Studying the effects of the microbiome on the development of different types of cancer has recently received increasing research attention. In this context, the microbial content of organs of the gastrointesti...
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Article
Identification of ZMYND19 as a novel biomarker of colorectal cancer: RNA-sequencing and machine learning analysis
Colorectal cancer (CRC) is the third most common cause of cancer-related deaths. The five-year relative survival rate for CRC is estimated to be approximately 90% for patients diagnosed with early stages and 1...
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Article
Bacterial Peptide and Bacteriocins in Treating Gynecological Cancers
After breast cancer, gynecological cancer is the most prevalent type of cancer in female population. The most frequently diagnosed types of gynecological cancers are cervical and ovarian cancer. Since the conv...
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Article
Seed burial depth, seedling emergence, and height as affected by animal trampling in marl soils
Depending on the plant species, animal trampling significantly affects vegetation by affecting seed burial in marl soil (MS). Soil seed bank dynamics (SSBDs) and seedling characteristics were investigated unde...
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Article
Peptides with Dual Antimicrobial-Anticancer Activity Derived from the N-terminal Region of H. pylori Ribosomal Protein L1 (RpL1)
Whereas the traditional approaches of cancer therapy including radiotherapy, chemotherapy, and immunotherapy have failed to properly treat cancer due to the condition of the space inside the tumor with the hyp...
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Article
The association between genetic variants in the genes for cytochrome P450 B1 and ATP-binding cassette transporter genes and breast cancer risk
Breast cancer is among the most common malignancies in women. Recent studies have shown that polymorphisms in genes involved in the metabolism and transport of anticancer drugs are associated with outcomes of ...
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Chapter
Therapeutic Potential of Heat Shock Protein 90 Inhibitors in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common causes of cancer- related death globally. Despite recent advances in diagnosis and treatment, CRC remains one of the leading cause mortality, with 5 years surv...
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Article
Open AccessAcute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits
Exaggerated postprandial spikes in blood glucose and lipids induce proportional increases in oxidative stress, which acutely trigger impairment endothelial, inflammation and increased risk of future cardiovasc...