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Article
Open AccessRNA sequencing identifies key genes involved in intramuscular fat deposition in chickens at different developmental stages
Intramuscular fat (IMF) is an important factor in meat quality, and triglyceride (TG) and Phospholipids (PLIP), as the main components of IMF, are of great significance to the improvement of meat quality.
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Article
Open AccessIntegrated analysis of the methylome and transcriptome of chickens with fatty liver hemorrhagic syndrome
DNA methylation, a biochemical modification of cytosine, has an important role in lipid metabolism. Fatty liver hemorrhagic syndrome (FLHS) is a serious disease and is tightly linked to lipid homeostasis. Here...
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Article
Open AccessIdentification of diverse cell populations in skeletal muscles and biomarkers for intramuscular fat of chicken by single-cell RNA sequencing
The development of skeletal muscle is closely related to the efficiency of meat production and meat quality. Chicken skeletal muscle development depends on myogenesis and adipogenesis and occurs in two phases—...
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Article
Open AccessA new chicken 55K SNP genoty** array
China has the richest local chicken breeding resources in the world and is the world’s second largest producer of meat-type chickens. Development of a moderate-density SNP array for genetic analysis of chicken...
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Article
Open AccessIntramuscular preadipocytes impede differentiation and promote lipid deposition of muscle satellite cells in chickens
Skeletal muscle satellite cells (MSC) are crucial for postnatal growth and regeneration of skeletal muscle. An interaction exists between MSC and intramuscular preadipocytes (IMPA). This study is the first to ...
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Article
Open AccessDecreased testosterone levels after caponization leads to abdominal fat deposition in chickens
Caponization results in reduced androgen levels, which leads to abdominal fat accumulation in capons. In this study, we sought to understand the molecular mechanisms behind this fat accumulation.
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Article
Open AccessIdentification of differentially expressed genes and pathways for intramuscular fat metabolism between breast and thigh tissues of chickens
Intramuscular fat (IMF) is one of the important factors influencing meat quality, however, for chickens, the molecular regulatory mechanisms underlying this trait have not yet been clear. In this study, a syst...
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Article
Open AccessUncovering the embryonic development-related proteome and metabolome signatures in breast muscle and intramuscular fat of fast-and slow-growing chickens
Skeletal muscle development is closely linked to meat production and its quality. This study is the first to quantify the proteomes and metabolomes of breast muscle in two distinct chicken breeds at embryonic ...
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Article
Changes of host DNA methylation in domestic chickens infected with Salmonella enterica
Cytosine methylation is an effective way to modulate gene transcription. However, very little is known about the epigenetic changes in the host that is infected with Salmonella enterica. ...
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Article
Identification of loci and genes for growth related traits from a genome-wide association study in a slow- × fast-growing broiler chicken cross
Identification of functional genes for multifactorial traits is an ongoing priority. A genome-wide association study and gene expression study for weight and carcass composition traits is presented here using...
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Article
A genome-wide detection of copy number variation using SNP genoty** arrays in Bei**g-You chickens
Copy number variation (CNV) has been recently examined in many species and is recognized as being a source of genetic variability, especially for disease-related phenotypes. In this study, the PennCNV software...
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Article
Open AccessThe identification of 14 new genes for meat quality traits in chicken using a genome-wide association study
Meat quality is an important economic trait in chickens. To identify loci and genes associated with meat quality traits, we conducted a genome-wide association study (GWAS) of F2 populations derived from a loc...