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Article
Open AccessRNA sequencing identifies key genes involved in intramuscular fat deposition in chickens at different developmental stages
Intramuscular fat (IMF) is an important factor in meat quality, and triglyceride (TG) and Phospholipids (PLIP), as the main components of IMF, are of great significance to the improvement of meat quality.
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Article
Open AccessA heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens
Quantification of leukocyte profiles is among the simplest measures of animal immune function. However, the relationship between H/L ratio and innate immunity and the measure’s utility as an index for heteroph...
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Article
Open AccessA significant quantitative trait locus on chromosome Z and its impact on egg production traits in seven maternal lines of meat-type chicken
Egg production is economically important in the meat-type chicken industry. To better understand the molecular genetic mechanism of egg production in meat-type chicken, genetic parameter estimation, genome-wid...
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Article
Open AccessIdentification of QTL regions and candidate genes for growth and feed efficiency in broilers
Feed accounts for about 70% of the total cost of poultry meat production. Residual feed intake (RFI) has become the preferred measure of feed efficiency because it is phenotypically independent of growth rate ...
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Article
Open AccessIntegrated analysis of the methylome and transcriptome of chickens with fatty liver hemorrhagic syndrome
DNA methylation, a biochemical modification of cytosine, has an important role in lipid metabolism. Fatty liver hemorrhagic syndrome (FLHS) is a serious disease and is tightly linked to lipid homeostasis. Here...
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Article
Open AccessIdentification of diverse cell populations in skeletal muscles and biomarkers for intramuscular fat of chicken by single-cell RNA sequencing
The development of skeletal muscle is closely related to the efficiency of meat production and meat quality. Chicken skeletal muscle development depends on myogenesis and adipogenesis and occurs in two phases—...
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Article
Open AccessNew insights into the associations among feed efficiency, metabolizable efficiency traits and related QTL regions in broiler chickens
Improving the feed efficiency would increase profitability for producers while also reducing the environmental footprint of livestock production. This study was conducted to investigate the relationships among...
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Article
Open AccessChicken gga-miR-1306-5p targets Tollip and plays an important role in host response against Salmonella enteritidis infection
Increasing evidence indicates that microRNAs (miRNAs) are involved in inflammatory response and immune regulation following pathogen invasion. The purpose of this study was to elucidate the roles played by Gallus...
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Article
Open AccessA new chicken 55K SNP genoty** array
China has the richest local chicken breeding resources in the world and is the world’s second largest producer of meat-type chickens. Development of a moderate-density SNP array for genetic analysis of chicken...
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Article
Open AccessIntramuscular preadipocytes impede differentiation and promote lipid deposition of muscle satellite cells in chickens
Skeletal muscle satellite cells (MSC) are crucial for postnatal growth and regeneration of skeletal muscle. An interaction exists between MSC and intramuscular preadipocytes (IMPA). This study is the first to ...
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Article
Open AccessDecreased testosterone levels after caponization leads to abdominal fat deposition in chickens
Caponization results in reduced androgen levels, which leads to abdominal fat accumulation in capons. In this study, we sought to understand the molecular mechanisms behind this fat accumulation.
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Article
Open AccessIdentification of differentially expressed genes and pathways for intramuscular fat metabolism between breast and thigh tissues of chickens
Intramuscular fat (IMF) is one of the important factors influencing meat quality, however, for chickens, the molecular regulatory mechanisms underlying this trait have not yet been clear. In this study, a syst...
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Article
Open AccessUncovering the embryonic development-related proteome and metabolome signatures in breast muscle and intramuscular fat of fast-and slow-growing chickens
Skeletal muscle development is closely linked to meat production and its quality. This study is the first to quantify the proteomes and metabolomes of breast muscle in two distinct chicken breeds at embryonic ...
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Article
Open AccessThe regulation of IMF deposition in pectoralis major of fast- and slow- growing chickens at hatching
The lipid from egg yolk is largely consumed in supplying the energy for embryonic growth until hatching. The remaining lipid in the yolk sac is transported into the hatchling’s tissues. The gene expression pro...
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Article
Changes of host DNA methylation in domestic chickens infected with Salmonella enterica
Cytosine methylation is an effective way to modulate gene transcription. However, very little is known about the epigenetic changes in the host that is infected with Salmonella enterica. ...
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Article
Open AccessHigh-salt intake negatively regulates fat deposition in mouse
High-salt (HS) intake contributes to hypertension and cardiopathy, but the effect of HS on fat deposition is controversial. Feed intake, fat mass, the percentage of abdominal fat, heat production, rate of oxyg...
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Article
Identification of loci and genes for growth related traits from a genome-wide association study in a slow- × fast-growing broiler chicken cross
Identification of functional genes for multifactorial traits is an ongoing priority. A genome-wide association study and gene expression study for weight and carcass composition traits is presented here using...
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Article
A genome-wide detection of copy number variation using SNP genoty** arrays in Bei**g-You chickens
Copy number variation (CNV) has been recently examined in many species and is recognized as being a source of genetic variability, especially for disease-related phenotypes. In this study, the PennCNV software...
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Article
Open AccessThe identification of 14 new genes for meat quality traits in chicken using a genome-wide association study
Meat quality is an important economic trait in chickens. To identify loci and genes associated with meat quality traits, we conducted a genome-wide association study (GWAS) of F2 populations derived from a loc...
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Article
Association of polymorphisms in adipocyte fatty acid binding protein gene with fat-related traits in chicken
PCR-SSCP analysis was used to detect polymorphic sites in chicken adipocyte fatty acid binding protein (A-FABP) gene. Six Chinese local breeds, Bei**g-You chicken, Dwarf chicken, Taihe silky chicken, Chongrenma ...
