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Article
Open AccessSplanchnic vein thrombosis in myeloproliferative neoplasms: risk factors for recurrences in a cohort of 181 patients
We retrospectively studied 181 patients with polycythaemia vera (n=67), essential thrombocythaemia (n=67) or primary myelofibrosis (n=47), who presented a first episode of splanchnic vein thrombosis (SVT). Budd–C...
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Article
High rate of recurrent venous thromboembolism in patients with myeloproliferative neoplasms and effect of prophylaxis with vitamin K antagonists
The optimal duration of treatment with vitamin K antagonists (VKA) after venous thromboembolism (VTE) in patients with Philadelphia-negative myeloproliferative neoplasms (MPNs) is uncertain. To tackle this iss...
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Article
Mutational profile of childhood myeloproliferative neoplasms
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Article
Open AccessPractice-relevant revision of IPSET-thrombosis based on 1019 patients with WHO-defined essential thrombocythemia
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Article
Open AccessSurvival and prognosis among 1545 patients with contemporary polycythemia vera: an international study
Under the auspices of an International Working Group, seven centers submitted diagnostic and follow-up information on 1545 patients with World Health Organization-defined polycythemia vera (PV). At diagnosis, ...
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Article
Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria
In an international study of 1104 patients with essential thrombocythemia (ET), a histological review according to the 2008 World Health Organization (WHO) criteria confirmed ET in 891 patients (WHO-ET, 81%), ...
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Article
Blood oxidative status and selectins plasma levels in healthy donors receiving granulocyte-colony stimulating factor
Recombinant human G-CSF (rHuG-CSF) is used for hematopoietic progenitor cells (HPC) mobilization and collection. Activation of polymorphonuclear leukocytes (PMN) is present during rHuG-CSF treatment and is ass...
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Article
Myocardial Infarction, Other Arterial Thrombosis and Invasive Coronary Procedures, in Hemaophilia B: A Critical Evaluation of Reported Cases
Myocardial infarction and other arterial thrombosis are commonly maintained to be rare in hemophilia patients. This, in general, seems true but the occurrence of a thrombotic event in hemophilia B is not excep...
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Article
The Occasional Venous Thromboses Seen in Patients with Severe (Homozygous) FXII Deficiency are Probably Due to Associated Risk Factors: A Study of Prevalence in 21 Patients and Review of the Literature
According to our personal experience and to the study of the literature, 11 cases of venous thrombosis have been described as sporadic reports in patients with severe (homozygous) factor XII (FXII) deficiencie...
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Article
Association of monoclonal gammopathy and polycythemia vera or essential thrombocythemia: study of a large cohort of patients
Concomitant cases of monoclonal gammopathies with polycythemia vera (PV) and essential thrombocythemia (ET) have been described. We report our experience in a large cohort of patients with ET and PV and the oc...
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Article
Antiplatelet glycoprotein autoantibodies in patients with autoimmune diseases with and without thrombocytopenia
The presence and specificity of antiplatelet autoantibodies in 32 patients with primary and 18 patients with secondary autoimmune thrombocytopenic purpura (AITP), as well as 11 nonthrombocytopenic patients wit...
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Article
Thrombocytosis in young people: Evaluation of 57 cases diagnosed before the age of 40
Over the past 13 years 57 cases of primary thrombocytosis in young people have been studied. Only patients with a platelet count over 500×109/liter and a follow-up longer than 2 years were considered. Thrombocyto...
