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  1. Article

    Open Access

    UV light-blocking contact lenses protect against short-term UVB-induced limbal stem cell niche damage and inflammation

    UVB irradiation has been linked to pathogenesis of pterygium, a conjunctival tumor growing onto transparent cornea, the windscreen of the eye. Due to corneal anatomy, ambient UVB irradiation is amplified at th...

    M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss in Scientific Reports (2018)

  2. No Access

    Article

    Stammzell-basierter biologischer Gefäßersatz

    Eine chronisch-kritische Ischämie bei Patienten mit zugrunde liegender arterieller Verschlusskrankheit erfordert rekonstruktive vaskuläre chirurgische Eingriffe, die bislang mit körpereigenen Venensegmenten od...

    Prof. Dr. M. Gasser, M. H. Frank, A. M. Waaga-Gasser in Gefässchirurgie (2018)

  3. Article

    Open Access

    Positional OSA part 2: retrospective cohort analysis with a new classification system (APOC)

    In Part 1 of this two-part article, the Amsterdam Positional Obstructive Sleep Apnoea Classification (APOC) was recently introduced, a classification system aimed at facilitating the identification of suitable...

    M. J. L. Ravesloot, M. H. Frank, J. P. van Maanen, E. A. Verhagen in Sleep and Breathing (2016)

  4. No Access

    Article

    Positional OSA part 1: towards a clinical classification system for position-dependent obstructive sleep apnoea

    In 1984, Cartwright suggested that physicians should differentiate between patients with either positional obstructive sleep apnoea (POSA) or non-positional OSA. Treatment of POSA has advanced dramatically rec...

    M. H. Frank, M. J. L. Ravesloot, J. P. van Maanen, E. Verhagen in Sleep and Breathing (2015)

  5. No Access

    Chapter and Conference Paper

    Identification of pancreatic cancer initiating cells: The role of the MDR gene ABCB5

    Tumor initiation and growth result from the formation of cancer initiating cells, also known as cancer stem cells (CSC). ABCB5 is a novel human multidrug resistance mediator. We recently showed that ABCB5 iden...

    Priv.-Doz. Dr. med. M. Gasser, M. Grimm in Chirurgisches Forum und DGAV Forum 2009 (2009)

  6. No Access

    Chapter and Conference Paper

    Chronic inflammation and tumor progression: Analysis of Toll-like receptor expression in colorectal carcinoma

    Chronic inflammation and infection are the most important epigenetic and environmental factors leading to tumorigenesis and tumor progression. The Toll-like receptor (TLR) family is a group of receptors involv...

    Dr. M. Grimm, M. H. Frank, N. Y. Frank in Chirurgisches Forum und DGAV Forum 2009 (2009)

  7. No Access

    Article

    Investigation of multidrug resistance in cultured human renal cell carcinoma cells by 31P-NMR spectroscopy and treatment survival assays

    KTCTL-26 and KTCTL-2 are renal cell carcinoma (RCC) lines with high and lowexpression of P-170 glycoprotein, respectively. Inherent differences between the two cell lines in terms of phosphate metabolites and ...

    N.W. Lutz, S.E. Franks, M.H. Frank, S. Pomer in Magnetic Resonance Materials in Physics, B… (2005)

  8. No Access

    Article

    X-ray structure analysis of a nickel-petroporphyrin confirms hypothesis of treibs

    G. G. Habermehl, G. Springer, M. H. Frank in Naturwissenschaften (1984)