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Article
Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial
Probiotics are commonly used after bariatric surgery; however, uncertainty remains regarding their efficacy. Our aim was to compare the effect of probiotics vs placebo on hepatic, inflammatory and clinical out...
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Article
Community Gardens as Environmental Health Interventions: Benefits Versus Potential Risks
The purpose of this paper was to summarize current findings on community gardens relevant to three specific areas of interest as follows: (1) health benefits, (2) garden interventions in develo** versus deve...
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Article
Open AccessSelective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons
The retinitis pigmentosa GTPase regulator (RPGR) and nephrocystin-4 (NPHP4) comprise two key partners of the assembly complex of the RPGR-interacting protein 1 (RPGRIP1). Mutations in RPGR and NPHP4 are linked to...
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Article
Development of functional assays for BRCA1 missense mutations
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Article
Recovery of viable CD34+ cells from cryopreserved hemopoietic progenitor cell products
The number of CD34+ cells infused into patients at the time of autologous or allogeneic transplantation is a clinically important variable, but the viability of these cells has not been extensively documented. In...
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Article
Combining ERBE and ISCCP data to assess clouds in the Hadley Centre, ECMWF and LMD atmospheric climate models
This study compares radiative fluxes and cloudiness fields from three general circulation models (the HadAM4 version of the Hadley Centre Unified model, cycle 16r2 of the ECMWF model and version LMDZ 2.0 of t...
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Article
The teratogenicity of cadmium-metallothionein in the rat
A single dose in the range 0.25–1.0 mg metallothionein-bound cadmium (MT-Cd)/kg body weight, when administered parenterally to the rat between day 8 and day 14 of gestation (gd 8–gd 14), is teratogenic. In vit...
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Article
Teratogenicity of ionic cadmium in the Wistar rat
In rats of the present (re-derived) Wistar-Porton strain that are dosed either intravenously (i.v.), or intraperitoneally (i.p.) with Cd (1.25 mg/kg body weight) on day 12 of gestation (gd 12), foetal uptake o...
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Chapter
Nomenclature of Metallothionein
The original recommendations concerning the nomenclature of metallothionein were made by the plenum of the First International Meeting on Metallothionein and Other Low Molecular Weight Metal-binding Proteins i...
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Article
Hypogammaglobulinaemia and malakoplakia: response to bethanechol
A second patient is described with the syndrome of hypogammaglobulinaemia and malakoplakia; he too responded dramatically to bethanechol treatment and remains well on it.
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Article
The toxicity and teratogenicity of mercuric mercury in the pregnant rat
Mercuric mercury (Hg2+), when injected IV into the pregnant Wistar rat, is retained mainly in the maternal compartment and uptake by the conceptuses is small. Thus if the dose is based on total body weight, the m...
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Article
Comparison of some biochemical effects of teratogenic doses of mercuric mercury and cadmium in the pregnant rat
Mercuric mercury (Hg2+), like cadmium (Cd2+), interferes with the transport of certain essential metals to the conceptus in the pregnant Wistar rat and, at 48 h after the IV injection of a teratogenic dose (0.79 ...
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Chapter
Role of Metallothionein in Cadmium Metabolism
Induction of the synthesis of the metal-binding protein, thionein, is not only a particularly interesting feature of the biochemistry of the cadmium (Cd) ion, but also of considerable importance in relation to...
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Article
The chronic toxicity of equine cadmium metallothionein in the rat
The extensive renal tubular necrosis that results in male rats after the intravenous injection of a single, low dose of equine kidney cadmium (Cd), zinc(Zn)-metallothionein (MT) (0.2 mg MT-bound-Cd/kg body wt....
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Article
Histological demonstration of immunoreactive zinc metallothionein in liver and ileum of rat and man
A sensitive immunohistochemical technique was used to demonstrate zinc metallothionein in rat and human liver and ileum. In the liver, immunoreactivity was observed within the hepatocyte nucleus and cytoplasm,...
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Chapter
Studies on the Structure and Function of the MoFe Protein of Nitrogenase
Analysis of the iron molybdenum center of nitrogenase, called FeMo-co, shows it to contain Mo, Fe and sulfur. EXAFS analysis has shown that this Mo center has ligands of Fe and S and a structure with four or f...
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Article
Intestinal and hepatic binding of cadmium in the neonatal rat
At 18 h after intragastric administration of 0.1 mg cadmium (Cd)/kg body weight to the 8-day-old rat, systemic absorption is small and at least 95% of the body burden (70% of the dose) is retained in the intes...
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Chapter and Conference Paper
Metallothionein and Its Relationship to the Toxicity of Cadmium and Other Metals in the Young
As the cadmium ion is cumulative and its transfer through the food chains cannot be avoided, long-lived animals species, even in uncontaminated environments, can accumulate appreciable body-burdens of the meta...
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Article
Responses of menstrual women, amenorrheal women, and men to exercise in a hot, dry environment
Rectal (Tre) and mean skin temperatures, heart rate (fc) and sweat rate (Msw) during exercise in a hot, dry environment were compared among four menstrual women (both before and after ovulation), four amenorrheal...
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Article
Endogenous metal binding proteins in relation to the differences in absorption and distribution of mercury in newborn and adult rats
Both in the intestinal copper complex and hepatic zinc-thionein of the newborn rat provide immediately available, high-affinity binding sites for Hg2+. Retention of orally administered Hg2+ in the gastrointestina...
