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  1. Article

    Open Access

    De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females

    Variants in CLCN4, which encodes the chloride/hydrogen ion exchanger CIC-4 prominently expressed in brain, were recently described to cause X-linked intellectual disability and epilepsy. We present detailed pheno...

    E E Palmer, T Stuhlmann, S Weinert, E Haan, H Van Esch, M Holvoet in Molecular Psychiatry (2018)

  2. No Access

    Article

    A large-deformation multiplicative framework for anisotropic elastoplastic materialswith application to sheet metal forming

    In this work, we discuss the derivation and the numerical implementation of a finite strain material model for plastic anisotropy and nonlinear kinematic and isotropic hardening. The model is derived in a ther...

    I. N. Vladimirov, M. Schwarze, M. P. Pietryga in International Journal of Material Forming (2010)

  3. No Access

    Article

    Anisotropic finite plasticity based on structural tensors—different strategies and application to forming simulations

    The accuracry of sheet metal forming crucially relies on the quality of the material description which involves the modelling of large strains, elastic and plastic anisotropy as well as different kinds of hard...

    S. Reese, M. P. Pietryga, I. N. Vladimirov in International Journal of Material Forming (2009)