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  1. No Access

    Article

    Comparative evaluation of the novel IMMUNOCATCHTM Streptococcus pneumoniae (EIKEN CHEMICAL CO., LTD) test with the Uni-GoldTM Streptococcus pneumoniae assay and the BinaxNOW® Streptococcus pneumoniae antigen card for the detection of pneumococcal capsular antigen in urine samples

    Community-acquired pneumonia (CAP) is one of the major causes of morbidity, mortality and hospitalization, and S. pneumoniae is the most frequently isolated etiologic agent. The pneumococcal urinary antigen test ...

    F. Congestrì, M. Morotti, R. Vicari in European Journal of Clinical Microbiology … (2020)

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    Article

    Multicenter performance evaluation of the Unyvero IAI cartridge for detection of intra-abdominal infections

    Intra-abdominal infections (IAIs) are one of the most common type of infections in patients with sepsis and an important cause of death in intensive care units. Early detection and treatment are necessary to r...

    H. Ciesielczuk, M. Wilks, S. Castelain in European Journal of Clinical Microbiology … (2018)

  3. Article

    Open Access

    The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer

    The availability of bromodomain and extra-terminal inhibitors (BETi) has enabled translational epigenetic studies in cancer. BET proteins regulate transcription by selectively recognizing acetylated lysine res...

    L L da Motta, I Ledaki, K Purshouse, S Haider, M A De Bastiani, D Baban in Oncogene (2017)

  4. Article

    Erratum: Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

    Correction to: Oncogene advance online publication, 24 November 2014; doi:10.1038/onc.2014.378 Following the online publication of this article, the authors have noticed a misspelt surname: S Hider should read...

    H Choudhry, A Albukhari, M Morotti, S Haider, D Moralli, J Smythies, J Schödel in Oncogene (2015)

  5. Article

    Open Access

    Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

    Activation of cellular transcriptional responses, mediated by hypoxia-inducible factor (HIF), is common in many types of cancer, and generally confers a poor prognosis. Known to induce many hundreds of protein...

    H Choudhry, A Albukhari, M Morotti, S Haider, D Moralli, J Smythies, J Schödel in Oncogene (2015)

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    Chapter

    Murine α/β Interferons Inhibit Benzo(A)Pyrene Activation and Mutagenesis in Mice

    In addition to their antiviral and immune regulatory properties, interferons (IFNs) are known to depress hepatic cytochrome P450-dependent metabolism. As many chemical mutagens and carcinogens require bioactiv...

    P. Hrelia, M. Morotti, F. Vigagni, F. Maffei in Antimutagenesis and Anticarcinogenesis Mec… (1993)

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    Chapter

    The Direct-Acting Mutagenicity of Nitrothiophenes Derivatives in Salmonella Typhimurium

    Nitroheterocyclic drugs have in recent years become of great interest for their mutagenicity and carcinogenicity. A series of nitrocompounds (structurally-related to the 5-nitro-3-thiophenecarboxylic acid) wer...

    P. Hrelia, M. Morotti, M. Scotti, M. Paolini, D. Spinelli, Forti G. Cantelli in Nitroarenes (1990)