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Article
Open AccessBiomarker alterations associated with distinct patterns of metastatic spread in colorectal cancer
Metastatic spread is the most important life-threatening feature of colorectal cancer and is supposed to be mainly driven by alterations in different carcinogenic pathways. The present study compared mutation ...
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Article
AIO-MentorUs – gelebte Nachwuchsförderung in der AIO
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Article
Impact of Baseline Cholinesterase in Patients with Primary Liver Tumors Undergoing Radioembolization: Impact on Outcome
The purpose of our study was to determine cutoff values for baseline cholinesterase (CHE) and bilirubin levels prognostic for outcome after radioembolization (RE) in patients with primary liver tumors. In this...
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Chapter
Third and Fifth Harmonic Responses in Viscous Liquids
We review the works devoted to third and fifth harmonic susceptibilities in glasses, namely \(\chi _3^{(3)}\) and ...
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Chapter
Nonlinear Dielectric Response of Plastic Crystals
This article summarizes ongoing experimental efforts on nonlinear dielectric spectroscopy on plastic crystals. In plastic crystals, the relevant dipolar orientational degrees of freedom are fixed on a crystall...
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Article
Investigation of nonlinear effects in glassy matter using dielectric methods
We summarize current developments in the investigation of glassy matter using nonlinear dielectric spectroscopy. This work also provides a brief introduction into the phenomenology of the linear dielectric re...
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Article
Tumor markers CEA and CA 19-9 correlate with radiological imaging in metastatic colorectal cancer patients receiving first-line chemotherapy
In patients with metastatic colorectal cancer (mCRC), radiological imaging represents the current standard to evaluate the efficacy of chemotherapy. However, with growing knowledge about tumor biology, other d...
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Article
Open AccessLeft-sided primary tumors are associated with favorable prognosis in patients with KRAS codon 12/13 wild-type metastatic colorectal cancer treated with cetuximab plus chemotherapy: an analysis of the AIO KRK-0104 trial
AIO KRK-0104 investigated first-line therapy of metastatic colorectal cancer (mCRC) with cetuximab, capecitabine and irinotecan versus cetuximab, capecitabine and oxaliplatin. This analysis investigated the im...