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Open AccessMetabolomic associations of impaired awareness of hypoglycaemia in type 1 diabetes
This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes. The exact pathophysiology is unclear, therefore we sou...
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Article
Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals
Genetic pleiotropy may contribute to the clustering of obesity and metabolic conditions. We assessed whether genetic variants that are robustly associated with BMI and waist-to-hip ratio (WHR) also influence m...
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Article
De nieuwe ADA/EASD-consensus type 2 diabetes en wat u daarvan moet weten
De behandeling van type 2 diabetes wordt meer en meer complex. Enerzijds is dat vanwege de multimorbiditeit die patiënten met type 2 diabetes zo kenmerkt. Het gaat dan niet alleen om type 2 diabetes met eventu...
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Article
PS18 - 86. Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals
Obesity is a key risk factor for a number of metabolic diseases, including type 2 diabetes, dyslipedimia and cardiovascular disease. Although the exact biological mechanisms linking obesity to these co-morbidi...
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Neuro-psychiatric effects of antimalarials
Objective: To study the neuro-psychiatric adverse effects of antimalarial drugs.
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Abstracts of papers clinical pharmacological meeting