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  1. No Access

    Article

    A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer

    Constitutive activation of the Wnt/β-catenin pathway has been implicated as the primary cause of colon cancer. However, the major transducers of Wnt signaling in the intestine, T-cell factor 1 (TCF-1) and TCF-...

    R Najdi, A Syed, L Arce, H Theisen, J-HT Ting, F Atcha, A V Nguyen, M Martinez… in Oncogene (2009)

  2. No Access

    Article

    Diversity of LEF/TCF action in development and disease

    Lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) mediate Wnt signals in the nucleus by recruiting β-catenin and its co-activators to Wnt response elements (WREs) of target genes. This activity is import...

    L Arce, N N Yokoyama, M L Waterman in Oncogene (2006)