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    Chapter

    Identifizierung von Chemosensitivität bei menschlichen Tumorzellen durch flavinschützende Tests in vitro

    Die Tendenz zur Resistenzentwicklung ist beim Bronchialkarzinom geradezu universell ausgeprägt (Carney 1995). Nur etwa 30% der chemotherapierten Patienten mit diesem Tumor profitieren von der Chemotherapie (Dr...

    C. Granzow, P. Drings, M. Kopun in Thoraxtumoren (1998)

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    Article

    Scientific Proceedings Second International Symposium on Cytostatic Drug Resistance

    Bridget T. Hill, L. K. Hosking, S. McClean in Journal of Cancer Research and Clinical On… (1991)

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    Chapter

    Genomveränderungen und Multidrogenresistenz von menschlichen Lungenkarzinomzellen

    Erworbene zelluläre Resistenz gegen Zytostatika ist häufig durch Amplifikation und Überexpression von Genen mit resistenzvermittelnden Produkten bedingt. Dies wurde erstmals bei Leukämiezellen mit Resistenz ge...

    C. Granzow, P. Drings, M. Kopun in Thoraxtumoren (1991)

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    Article

    Absract

    Marietta Kaszkin, Volker Kinzel, Karl Maly in Journal of Cancer Research and Clinical On… (1991)

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    Chapter

    Abstracts of Selected Posters

    The analysis of chromosomes of mouse embryos permits detection of transmitted chromosome damage. The protocol involves the treatment of one parent (usually the male) with a clastogen, recovery of embryos and p...

    R. Albanese, J. L. Antoine, B. Dutrillaux, T. Ashley, L. Avivi in Chromosomes Today (1984)

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    Article

    The kinetics of ethanol absorption and elimination in twins and supplementary repetitive experiments in singleton subjects

    The influence of genetic and environmental factors on the metabolism of a single oral dose of ethanol 1.2 ml per kg body weight was analysed in 19 identical and 21 fraternal healthy, adult, un-selected male tw...

    M. Kopun, P. Prop** in European Journal of Clinical Pharmacology (1977)

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    Article

    Higher frequencies of transitions among point mutations

    The problem of non-randomness of point mutations was reexamined using three sources of information:

    1. Amino acid replacements in...

    F. Vogel, M. Kopun in Journal of Molecular Evolution (1977)

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    Chapter

    Mutation and Molecular Evolution

    The mutation process provides all the genetic variants from which evolution selects the most useful in order to produce the present-day diversity of living organisms. Until recently, evolution theoreticians ha...

    F. Vogel, M. Kopun, R. Rathenberg in Molecular Anthropology (1976)