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Chapter
Model-Based Risk Assessment of mAb Developability
Monoclonal antibodies were already one of the fastest growing sectors of biopharmaceutical industry [1]. Recent research on the significant benefits of various antibodies in reducing the risks of fatality or redu...
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Chapter
Pathophysiology of Whiplash-Associated Disorders: Theories and Controversies
The term “whiplash” already suggests difficulties in assessing this problem. Patients suffering from “whiplash” or “whiplash-associated disorders” (WAD) are defined as having been exposed to similar types of t...
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Chapter and Conference Paper
Developments in Rotor Dynamical Modeling of Hydropower Units
During the last century the hydropower units have been developed from a few megawatts per unit, up to several hundreds megawatts per unit. Over the years the operating conditions have also been changed from th...
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Article
Open AccessPro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis
The process of apoptosis in immune cells like mast cells is essential to regain homeostasis after an inflammatory response. The intrinsic pathway of apoptosis is ultimately controlled by the pro-apoptotic Bcl-...
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Chapter and Conference Paper
Pathophysiology of Whiplash Associated Disorders: Theories and Controversies
The term “whiplash” already suggests difficulties in assessing this problem. Patients suffering from “whiplash” or “whiplash associated disorders” (WAD) are defined as having been exposed to similar types of t...
