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Article
Open AccessSystematic investigation of imprinted gene expression and enrichment in the mouse brain explored at single-cell resolution
Although a number of imprinted genes are known to be highly expressed in the brain, and in certain brain regions in particular, whether they are truly over-represented in the brain has never been formally test...
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Article
Ecological effects of a supra-seasonal drought on macroinvertebrate communities differ between near-perennial and ephemeral river reaches
The duration, intensity and frequency of hydrological droughts are predicted to increase significantly over the 21st century globally, threatening the long-term stability of lotic communities. In this paper we...
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Article
Open AccessCommunity heterogeneity of aquatic macroinvertebrates in urban ponds at a multi-city scale
Urbanisation is a leading cause of biotic homogenisation in urban ecosystems. However, there has been little research examining the effect of urbanisation and biotic homogenisation on aquatic communities, and ...
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Article
Open AccessMacroinvertebrate Taxonomic and Functional Trait Compositions within Lotic Habitats Affected By River Restoration Practices
The widespread degradation of lotic ecosystems has prompted extensive river restoration efforts globally, but many studies have reported modest ecological responses to rehabilitation practices. The functional ...
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Article
Open AccessMiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls
Variants at microRNA-137 (MIR137), one of the most strongly associated schizophrenia risk loci identified to date, have been associated with poorer cognitive performance. As microRNA-137 is known to regulate the ...
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Article
Open AccessAquatic macroinvertebrate biodiversity associated with artificial agricultural drainage ditches
Agricultural drainage ditches are ubiquitous features in lowland agricultural landscapes, built primarily to facilitate land drainage, irrigate agricultural crops and alleviate flood risk. Most drainage ditche...
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Article
Open AccessWhen is the best time to sample aquatic macroinvertebrates in ponds for biodiversity assessment?
Ponds are sites of high biodiversity and conservation value, yet there is little or no statutory monitoring of them across most of Europe. There are clear and standardised protocols for sampling aquatic macroi...
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Article
The aquatic macroinvertebrate biodiversity of urban ponds in a medium-sized European town (Loughborough, UK)
Urbanisation is one of the greatest threats to freshwater biodiversity, with the area of land covered by towns and cities predicted to increase significantly in the future. Ponds are common features in the urb...
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Article
Allelic differences in nuclear protein binding at a genome-wide significant risk variant for schizophrenia in ZNF804A
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Article
Some Observations on Induction in Predicate Probabilistic Reasoning
We consider the desirability, or otherwise, of various forms of induction in the light of certain principles and inductive methods within predicate uncertain reasoning. Our general conclusion is that there rem...
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Article
Chain-folding and structures in nylon 6 oligoamide lamellar crystals
A series of carefully selected monodisperse nylon 6 oligomers, terminated with short alkane segments, have been crystallised from solution. This contribution contains an overview of the folding and structures ...
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Article
The transmission of Fusarium subglutinans from maize seeds to seedlings
The transmission of Fusarium subglutinans from maize (Zea mays) seeds to seedlings has not been clearly demonstrated. The objectives of this study were to determine whether P. subglutinans is seed transmitted, an...
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Chapter
Dietary Fibre and Human Cancer
Burkitt (1969, 1971, 1973) postulated that dietary fibre was a major protective factor against colorectal carcinogenesis, based on his studies in Africa. He hypothesised that the carbohydrate that reached the ...
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Chapter
Anticarcinogens/Inhibitors in the Diet
It was natural that most of the early interest in carcinogenesis should have centred on the identification of the causes of cancer and the mechanisms by which they act. It is also self-evident that the study of i...
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Chapter
Final Conclusions
During the last two decades many groups have attempted to summarize the current knowledge on diet and cancer and to present the conclusions in the form of sets of guidelines. These have been reviewed here in t...
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Chapter and Conference Paper
The Role of Intestinal Microbes in Ulcerative Colitis: Studies on the Rectal Mucosa-Associated Microflora
There is broad agreement that microbes play an important role in the aetiology and pathogenesis of ulcerative colitis (UC), probably via an abnormal local immune response to one or several microbial antigens o...
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Chapter and Conference Paper
Development of a Reliable Measure for Determining Nitrate Exposure for Use in Epidemiological Studies
Regardless of dose or matrix, 24-h urinary nitrate reliably accounts for 50 to 60% of daily nitrate ingestion, except in those individuals who are immune stimulated and endogenously synthesize nitrate and thos...
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Chapter and Conference Paper
Faecal bile acids in pouch and pouchitis patients
In previous studies we have reported on the faecal bile acids in patients with chronic ulcerative colitis and in familial adenomatous polyposis (FAP) patients. In the former group of patients there was a relat...
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Chapter and Conference Paper
Bacteriology (II)
Chronic inflammation in the reservoir occurs in almost every case; acute inflammatory changes, often severe and associated with diarrhoea (pouchitis) occur in some colitic patients but not in those with polypo...
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Article
Abstracts