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Chapter
Molecular Chaperones in Signal Transduction
Many cellular signaling molecules exist in different conformations corresponding to active and inactive states. Transition between these states is regulated by reversible modifications, such asphosphorylation,...
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Chapter
sHsp-Phosphorylation: Enzymes, Signaling Pathways and Functional Implications
Several posttranslational modifications of sHsps have been detected, including phosphorylation (Kim et al. 1983; Voorter et al. 1986), deamidation, acylation as well as mixed intermolecular disulfide formation, o...
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Chapter and Conference Paper
Use of Fluorescence-Activated Cell Sorting to Select Hybrid Hybridomas Producing Bispecific Monoclonal Antibodies
Antibodies containing two different antigenbinding sites were prepared for the first time in 1961 by Nisonoff and Rivers [1] by dissociating two different antibodies and reassociating the mixture of half molec...