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Article
Open AccessA longitudinal characterization of the Non-Cystic Fibrosis Bronchiectasis airway microbiome
A diverse microbiota exists within the airways of individuals with non-cystic fibrosis bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes within the microbiome correlate with...
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Article
Open AccessBrain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis
Microbial communities reside in healthy tissues but are often disrupted during disease. Bacterial genomes and proteins are detected in brains from humans, nonhuman primates, rodents and other species in the ab...
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Article
Open AccessInfection control knowledge, beliefs and behaviours amongst cystic fibrosis patients with epidemic Pseudomonas aeruginosa
Epidemic P. aeruginosa (ePA) infections are common in cystic fibrosis (CF) and have been associated with accelerated clinical decline. Factors associated with ePA are unclear, and evidence based infection control...
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Article
Microbiota and host determinants of behavioural phenotype in maternally separated mice
Early-life stress is a determinant of vulnerability to a variety of disorders that include dysfunction of the brain and gut. Here we exploit a model of early-life stress, maternal separation (MS) in mice, to i...
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Article
Pyrosequencing reveals the complex polymicrobial nature of invasive pyogenic infections: microbial constituents of empyema, liver abscess, and intracerebral abscess
The polymicrobial nature of invasive pyogenic infections may be underestimated by routine culture practices, due to the fastidious nature of many organisms and the loss of viability during transport or from pr...
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Article
Robustness in bacterial chemotaxis
Networks of interacting proteins orchestrate the responses of living cells to a variety of external stimuli1, but how sensitive is the functioning of these protein networks to variations in theirbiochemical param...
