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Chapter
Hypoxia and Tumour Angiogenesis
The hypoxia-inducible factor (HIF) is a well-known transcription factor recognized to play a key role in tumour angiogenesis through a cellular response to a low tissue oxygen concentration, a feature of a rap...
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Article
Hypoxia and cancer
A major feature of solid tumours is hypoxia, decreased availability of oxygen, which increases patient treatment resistance and favours tumour progression. How hypoxic conditions are generated in tumour tissue...
