-
Article
Effects of 6 months of resveratrol versus placebo on pentraxin 3 in patients with type 2 diabetes mellitus: a double-blind randomized controlled trial
The anti-inflammatory effects of the polyphenol resveratrol in patients with type 2 diabetes mellitus (T2DM) are controversial. Its role on pentraxin 3 (PTX3) concentrations, a human acute phase protein, has ...
-
Article
Variations of serum levels of adiponectin and resistin in chronic viral hepatitis
Background and aims: Several studies investigated the possible role of adipokines during chronic viral hepatitis, not producing defined results neither clearly establishing their behavior in cour...
-
Article
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH): NAFLD causes an increased risk of cardiovascular disease, diabetes and li...
-
Article
Contributors to the obesity and hyperglycemia epidemics. A prospective study in a population-based cohort
Relatively unexplored contributors to the obesity and diabetes epidemics may include sleep restriction, increased house temperature (HT), television watching (TW), consumption of restaurant meals (RMs), use of...
-
Article
Associations between serum uric acid and adipokines, markers of inflammation, and endothelial dysfunction
Aim: Serum uric acid is associated with the metabolic syndrome and its components, while its relationship with cardiovascular disease is controversial. The aim of the study was to evaluat...
-
Article
Low-density lipoproteins are more electronegatively charged in type 1 than in type 2 diabetes mellitus
Multifactorial etiology is involved in premature atherosclerosis related to diabetes. Most of the mechanisms that are responsible for the etiology in diabetes have remained unsolved so far. Type 1 diabetes is ...
-
Article
C-reactive protein and tumor necrosis factor-α in gestational hyperglycemia
Objectives and study design: Increasing evidences support an inflammatory origin for gestational hyperglycemia. This paper aims at investigating, cross-sectionally and prospectively, the relation...
-
Article
Relationships between human serum resistin, inflammatory markers and insulin resistance
Data on the association of resistin levels with markers of insulin resistance are highly contrasting in humans and very few studies about its role in inflammation are available. This study investigates associa...
-
Article
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
Non-alcoholic fatty liver disease (NAFLD) has been associated with the metabolic syndrome. However, it is not clear whether insulin resistance is an independent feature of NAFLD, and it remains to be determine...
-
Article
40th EASD Annual Meeting of the European Association for the Study of Diabetes
-
Article
Platelet cGMP inversely correlates with age in healthy subjects
Biochemical modifications associated with the increase in platelet activity with age are not well defined. Furthermore it is well known that the nitric oxide/cyclic 3’, 5’-guanosine monophosphate (cGMP) pathwa...
-
Article
35th Annual Meeting of the European Association for the Study of Diabetes
-
Article
Effects of dietary cholesterol on plasma lipoproteins and their subclasses in IDDM patients
To compare the effects of dietary cholesterol supplementation in insulin-dependent diabetic (IDDM) patients and normal subjects, 10 male IDDM patients in good glycaemic control (HbA1 c 7.3 ± 0.9 %) (mean ± SD) a...
-
Article
Serum glucose, insulin and C-peptide response to oral glucose after intravenous administration of hydrocortisone and methylprednisolone in man
Glucocorticoid-induced glucose intolerance and insulin resistance are dependent on the type of steroid, its dose and route of administration. Although the intravenous (i.v.) route is used mainly, the effects o...
-
Article
Feedback inhibition of insulin and glucagon secretion by insulin is altered in abdominal obesity with normal or impaired glucose tolerance
We investigated the feedback inhibition of insulin and glucagon secretion during euglycemic-hyperinsulinemic clamp at about 350 pmol/l in 16 patients with abdominal obesity [8 with normal glucose tolerance (oN...
-
Article
Comparison of acute and subacute effects of deflazacort and prednisone on glucose metabolism in man
Corticosteroid treatment produces glucose intolerance with insulin resistance. Recent reports have indicated that deflazacort (DF) is significantly less diabetogenic than prednisone (PN). A euglycaemic hyperin...
