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Article
Phase 1 dose-escalation study of a siRNA targeting the RTP801 gene in age-related macular degeneration patients
To evaluate the safety, tolerability, pharmacokinetics, and dose-limiting toxicities of a single intravitreal (IVT) injection of PF-04523655, a 19-nucleotide, O-methyl stabilized, double-stranded small interferin...
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Article
Studying the electronic structure of Cr x Ti1−xSe2 by X-ray resonance and absorption spectroscopy
Cr x Ti1 − xSe2 (x = 0–0.83) solid solutions have been synthesized. Single crystals have been grown in the range of concentrations x = 0–0.83. Structural studies of samples have ...
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Article
The EC networking on elemental speciation revisited
In Europe, the EC-funded Thematic Network “Speciation 21” was instrumental in disseminating the existing knowledge about chemical speciation of trace elements. It created a forum in which analytical chemists w...
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Article
Orientierungshilfen an Biopsiepräparaten
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Article
CARS thermometry in a transversely heated graphite-tube atomizer used in atomic absorption spectrometry
An experimental setup for gas-temperature diagnostics using Coherent Anti-Stokes Raman Scattering (CARS) in very small sample volumes with great spatial and temporal temperature variations is presented. Studie...
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Article
225. Untersuchungen zur Pathogenese der katabolen Stoffwechsellage beim chirurgischen Risikopatienten
Non specific proteolytic (azocasein hydrolyzing) activity and non-TCA precipitable low-molecular-weight plasma protein concentration were elevated in the plasma of patients with polytrauma (n = 17) and operative ...
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Article
Abweichungen vom lokalen thermischen Gleichgewicht im axialen Kanal eines induktiv gekoppelten Argon-Plasmas
Measurement of the excited state level population of a thermometric species like FeI injected into the axial channel of an inductively coupled plasma (ICP) is a powerful method to describe the plasma, even whe...
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Article
ELEVATED CALCITONIN (CT) IN BIRTH ASPHYXIA AND PREMATURITY: ROLE IN THE PATHOGENESIS OF EARLY NEONATAL HYPOCALCEMIA (HC)
Although CT is stress responsive the role of CT in pathogenesis of early neonatal HC is unknown. We studied the thesis that CT, gastrin, glucagon 1) are higher in cord than mother; 2) rise postnatally; 3) corr...
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Chapter
Glucagon in the Fetus and the Newborn
In adult mammals, insulin and glucagon exert diametrically opposing actions upon hepatic metabolism (Unger and Orci 1981). Glucagon, through its powerful glycogenolytic and gluconeogenic effects on the liver, pro...
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Article
Endogenous Opiates Modulate Basal Hepatic Glucose Production
The endogenous opiates have effects on many hormone systems including insulin and glucagon, but their influence on glucose turnover is unknown. We examined the effect of naloxone, an opiate blocker, on glucose...
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Article
236 AN OVINE MODEL OP PETAL (F) HYPERINSULINEMIA — EFFECTS ON GLUCOSE (G) KINETICS
We used the chronically catheterized pregnant sheep in late gestation (130 ± 2D; term ∼150D) and simultaneous infusion of labeled G to mother (2-3H) and F (U-14C) to assess the effects of short term insulin (I) i...
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Article
1114 AN ACUTE MODEL OF THE FETUS (F) OF DIABETIC PREGNANCY (DP)
To gain insight into mechanisms responsible for disturbed CHO metabolism in DP, we acutely simulated F hyperglycemia and hyperinsulinemia in sheep (n=5) late in gestation (129 ± 1D; term ∼ 150D). Labeled gluco...
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Article
1644 THE DEVELOPMENT OF INSULIN RECEPTORS IN THE FETAL RABBIT LUNG
Recent studies demonstrated higher insulin (I) binding to various fetal tissues when compared to the adult. We investigated the status of I receptors in develo** fetal lung in rabbit. Plasma membranes were p...
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Chapter
Das Haemonetics-System — ein neues System zur Autotransfusion
Die intraoperative Autotransfusion mit dem Bentley ATS-System hat sich seit Jahren in unserer Klinik bewährt [1]. Es konnten jetzt erste Erfahrungen mit einem neuen System zur Autotransfusion, dem Haemonetics ...
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Article
Der Überdehnungsriß von Gefäßen als Komplikation alloarthroplastischer Operationen
The authors referred specific complications in the course of arthroplasties of the hip and of the knee: hyper-extending-ruptures of vessels in sequence of indirect lesions. Causes of these so far not described co...
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Article
Die Profundaplastik in der Behandlung arterieller Verschlußerkrankungen im Stadium IV
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Article
1b. Die subcutane arteriovenöse Fistel zur Kanülierung in der intermittierenden Hämodialysebehandlung
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Chapter and Conference Paper
Das Streifentransplantat zur Erweiterung von End-zu-End-Vereinigungen englumiger Gefäße
Große Bedeutung kommt der Wiedervereinigung englumiger Gefäße hauptsächlich bei Verletzungen paariger Extremitätenarterien oder engkalibriger Hauptschlagadern, z. B. der A. brachialis oder A. poplitea, zu.
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Article
Das Streifentransplantat zur Erweiterung von End-zu-End-Vereinigungen englumiger Gefäße
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