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Article
Open AccessNew Au/chitosan nanocomposite modified carbon paste sensor for voltammetric detection of nicotine
A profoundly touchy voltammetric sensor for detection of nicotine (NIC) in urine and tobacco specimens has been developed in light of the boosted electrochemical response of NIC at gold and chitosan nanocompos...
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Article
Open AccessSensitive detection for nicotine using nickel/copper nanoparticle–modified carbon paste electrode
The need of quick testing of nicotine (NIC) is vital because of its hurtful impacts on human. NIC detection has been successfully developed using a novel sensitive simple electrochemical sensor. The sensor sys...
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Article
Open AccessElectrochemical determination of vitamin B6 (pyridoxine) by reformed carbon paste electrode with iron oxide nanoparticles
This work aims to introduce a simple high-performance sensitive electrochemical sensor of reformed carbon paste (CP) with iron oxide nanoparticles (IONs). It was developed to determine one of the most importan...
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Article
Open AccessCitraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
Although the immunomodulatory and cytoprotective properties of itaconate have been studied extensively, it is not known whether its naturally occurring isomers mesaconate and citraconate have similar propertie...
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Chapter and Conference Paper
Efficient Modeling Procedure of Novel Grating Tiling Device Using Multibody System Approach
This paper proposes a multibody system (MBS) procedure for a novel aperture grating device which considered as a rigid-flexible multibody system. The MBS model is constructed based on the load assumptions due ...
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Chapter and Conference Paper
A Promising Non-invasive CAD System for Kidney Function Assessment
This paper introduces a novel computer-aided diagnostic (CAD) system for the assessment of renal transplant status that integrates image-based biomarkers derived from 4D (3D + b-value) diffusion-weighted (DW) MRI...
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Chapter and Conference Paper
Electrochemical Detection of Nicotine Using Cerium Nanoparticles Modified Carbon Paste Sensor and Anionic Surfactant
A promising electrochemical sensor for the determination of nicotine (NIC) was developed by electrodeposition of Ce-Nanoparticles on a carbon paste electrode (CPE). The interaction of nicotine was studied usin...
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Article
Induction of DNA double-strand breaks by monochlorophenol isomers and ChKM in human gingival fibroblasts
Phenol has been traditionally used in dental treatment as a sedative for the pulp or as disinfectant for carious cavity and root canal. However, phenol is regarded as a mutagenic and carcinogenic agent and its...
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Article
Open AccessUrinary neutrophil gelatinase-associated lipocalin as an early marker of acute kidney injury complicating circulatory shock
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Article
Sequential gene expression profiling during treatment for identification of predictive markers and novel therapeutic targets in chronic lymphocytic leukemia
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Article
Open AccessTopo2α protein expression predicts response to anthracycline combination neo-adjuvant chemotherapy in locally advanced primary breast cancer
This study aimed to identify predictors of response to anthracycline-based chemotherapy (5-fluoro-uracil, epirubicin, cyclophosphamide (FEC)) in locally advanced primary breast cancer (LAPC).
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Article
Thioredoxin and related redox systems as targets in breast cancer
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Article
Topoisomerase 2 alpha as a predictor of response to anthracycline neoadjuvant chemotherapy in locally advanced breast cancer
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Article
Clinical predictors of physiological deterioration
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Article
Impact of hypernatremia on patients with severe traumatic brain injury
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Article
Open AccessTreatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases – the UK experience
The global lapatinib expanded access programme provided access to lapatinib combined with capecitabine for women with HER2-positive metastatic breast cancer (MBC) who previously received anthracycline, taxane ...
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Article
Open AccessHuman apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers
Altered DNA repair may be associated with aggressive tumour biology and impact upon response to chemotherapy and radiotherapy. We investigated whether expression of human AP endonuclease (APE1), a key multifun...
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Article
Open AccessHuman leukocyte antigen class I expression is an independent prognostic factor in advanced ovarian cancer resistant to first-line platinum chemotherapy
Loss of HLA class I is important in ovarian cancer prognosis but its role as a prognostic indicator in relation to therapy remains unproven. We studied the prognostic potential of this antigen and its signific...
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Article
Open AccessNew cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis
To enable detailed analyses of cell interactions in tumour development, new epithelial and mesenchymal cell lines were established from human hepatocellular carcinoma by spontaneous outgrowth in culture. We ob...
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Article
Open AccessA newly developed tool for intra-tracheal temperature and humidity assessment in laryngectomized individuals: the Airway Climate Explorer (ACE)
The aim of this study is to develop a postlaryngectomy airway climate explorer (ACE) for assessment of intratracheal temperature and humidity and of influence of heat and moisture exchangers (HMEs). Engineerin...