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    Article

    Atypical mechanism of NF-κB activation by TRE17/ubiquitin-specific protease 6 (USP6) oncogene and its requirement in tumorigenesis

    The NF-κB transcription factor has a central role in diverse processes, including inflammation, proliferation and cell survival, and its activity is dysregulated in diseases such as autoimmunity and cancer. We...

    L M Pringle, R Young, L Quick, D N Riquelme, A M Oliveira, M J May, M M Chou in Oncogene (2012)

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    TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB

    Aneurysmal bone cyst (ABC) is an aggressive, pediatric bone tumor characterized by extensive destruction of the surrounding bone. Although first described over 60 years ago, its molecular etiology remains poor...

    Y Ye, L M Pringle, A W Lau, D N Riquelme, H Wang, T Jiang, D Lev, A Welman in Oncogene (2010)

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    Article

    Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-κB pathway

    Visfatin is an adipokine that is highly expressed in visceral fat. Plasma levels of visfatin have been reported to be higher in subjects with obesity and/or type 2 diabetes mellitus. However, the role of visfa...

    W-J Lee, C-S Wu, H Lin, I-T Lee, C-M Wu, J-J Tseng in International Journal of Obesity (2009)