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    Article

    Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079)

    Background This study investigated the activity of MK-2206, an AKT inhibitor, in metastatic or recurrent nasopharyngeal carcinoma (NPC). Method Oral MK-2206 at a dose of 200 mg was admini...

    B. B. Y. Ma, B. C. Goh, W. T. Lim, E. P. Hui, E. H. Tan… in Investigational New Drugs (2015)

  2. Article

    Perturbation of Hoxb5 signaling in vagal and trunk neural crest cells causes apoptosis and neurocristopathies in mice

    Neural crest cells (NCCs) migrate from different regions along the anterior–posterior axis of the neural tube (NT) to form different structures. Defective NCC development causes congenital neurocristopathies a...

    M K M Kam, M C H Cheung, J J Zhu, W W C Cheng, E W Y Sat… in Cell Death & Differentiation (2014)

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