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Article
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
The prosurvival Bcl-2-family member Bfl-1/A1 is a transcriptional target of nuclear factor-κB (NF-κB) that is overexpressed in many human tumors and is a means by which NF-κB inhibits apoptosis, but its mode o...
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Article
Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor
Bfl-1/A1 is generally recognized as a Bcl-2-related inhibitor of apoptosis. We show that Bfl-1 undergoes constitutive ubiquitin/proteasome-mediated turnover. Moreover, while Bfl-1 suppresses apoptosis induced ...
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Chapter and Conference Paper
An Investigation of Active, Suction, Shock and Boundary Layer Control Techniques
This report describes experimental and theoretical studies at high subsonic speeds on a two-dimensional airfoil of novel drag reduction systems. The control systems are all ‘active’ in the sense that they util...
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Chapter
An Experimental Investigation of Passive Shock/Boundary-Layer Control on an Aerofoil
An experiment at high subsonic speeds on a two-dimensional aerofoil model is described, with a passive system for the control of shock waves via a porous skin and under-surface cavity. Passive control utilises...