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Article
Correction to: Quantum Systems Simulatability Through Classical Networks
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Article
Quantum Systems Simulatability Through Classical Networks
We have shown that any two quantum systems on finite-dimensional Hilbert spaces are equivalent under local transformations. These transformations give rise to a gauge group that connects the hamiltonian operat...
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Chapter and Conference Paper
Critical Overview and Application of Integrated Approaches for Seismic Loss Estimation and Environmental Impact Assessment
Buildings are among the major contributors to environmental impacts, in terms of non-renewable resource depletion, energy and material consumption, and greenhouse gas (GHG) emissions. For this reason, modern s...
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Article
Monthly fluctuations in 25-hydroxy-vitamin D levels in day and rotating night shift hospital workers
Epidemiological studies have suggested that indoor hospital employees, either day or night shift workers, are at high risk of metabolic and cardiovascular diseases. Interestingly, previous reports have also de...
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Reference Work Entry In depth
The Electrochemistry of Peptide Self-Assembled Monolayers
The self-assembly ability of molecules is of fundamental importance in modern science and technology, making possible to produce nanostructures with a precision that is not achievable with classical lithograph...
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Living Reference Work Entry In depth
The Electrochemistry of Peptide Self-Assembled Monolayers
The self-assembly ability of molecules is of fundamental importance in modern science and technology, making possible to produce nanostructures with a precision that is not achievable with classical lithograph...
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Chapter and Conference Paper
Nanofabrication Tools and Techniques for Bio-inorganic Interfaces
This paper describes some progresses in the development of technical and biomimetic machineries for nanobiofabrication. Together with nanotechnological methods, both ready made natural nanostructures and the a...
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Chapter and Conference Paper
Spectroscopy and Electrochemistry of Peptide-Based Self-Assembled Monolayers
Mono and bi-component peptide-based self-assembled monolayers (SAMs) immobilized on a gold surface were studied by electrochemical and spectroscopic techniques. The peptides investigated were exclusively forme...
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Article
Gap junctions in human glioblastomas: implications for suicide gene therapy
Glioblastoma is a very aggressive astrocytic tumor and most patients have 1-year survival time after diagnosis. A promising therapeutic strategy is the local delivery of the herpes simplex virus thymidine kinase ...
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Article
Prediction of response to growth hormone treatment in pre-pubertal children with growth hormone deficiency
Background: GH therapy response varies substantially among patients. Several models were developed to predict the efficacy of GH therapy in children. Aim: To evaluate the accuracy of a gr...
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Article
Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43
Herpes simplex virus thymidine kinase (TK) gene transfer followed by ganciclovir (GCV) administration is an approach investigated for glioblastoma treatment. The bystander effect (BE) enhances the cytotoxic ef...
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Article
Investigation of the metabolic activity of a bovine mammary epithelial cell line (BME-UV1)
The metabolic activity of a mammary epithelial cell line (BME-UV1) was evaluated on monolayers exposed, in serum free medium, to different concentrations (2-4-8 μM) of aflatoxin B1 (AFB1), a mycotoxin eliminat...
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Article
Salt-wasting congenital adrenal hyperplasia: Genotypical peculiarities in a Sicilian ethnic group
Here we report for the first time the results of the molecular study of 17 unrelated patients with salt-wasting (SW) congenital adrenal hyperplasia (CAH) belonging to a Sicilian ethnic group, as corroborated b...
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Article
Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media
Several patients with severe combined immunodeficiency-X1 disease and adenosine deaminase deficiency have been cured by retroviral-mediated gene therapy. Despite the earlier success, the production of retrovir...
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Article
In Sicilian ethnic group non-classical congenital adrenal hyperplasia is frequently associated with a very mild genotype
The spectrum of mutated alleles in non-classical congenital adrenal hyperplasia (NC-CAH) has been recently reported to be very large and haplotypes may significantly differ in the different ethnic groups. In o...
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Article
VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment
Low levels of gene delivery in vivo using replication-defective retroviral vectors have severely limited their application for clinical protocols. To overcome this problem, we describe here a semi-replication-com...
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Article
Cellular and molecular effects of protons: Apoptosis induction and potential implications for cancer therapy
Due to their ballistic precision, apoptosis induction by protons could be a strategy to specifically eliminate neoplastic cells. To characterize the cellular and molecular effects of these hadrons, we performe...
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Article
Salt wasting phenotype in a compound heterozygous girl with P482S mutation associated with a novel mutation of CYP21 gene (Q481P)
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Article
Direct evidence for the absence of intercellular trafficking of VP22 fused to GFP or to the herpes simplex virus thymidine kinase
The treatment of solid tumors by retroviral delivery of the herpes simplex virus thymidine kinase (TK) followed by ganciclovir (GCV) treatment has so far shown only limited success in patients. One major drawb...
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Article
Analysis of stable carbon and nitrogen isotopes as a tool for assessing the environmental impact of aquaculture: a case study from the western Mediterranean
Stable carbon and nitrogen isotope ratios ( 13C/ 12 C and 15N/14 N) of in situ dominant primary producers and consumers were investigated to assess the impact on a natural ecosystem of a land-based fish farm alon...