22 Result(s)

Article

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy

AXL receptor tyrosine kinase (RTK) is implicated in proliferation and invasion of many cancers, particularly in pancreatic ductal adenocarcinoma (PDAC), for which new therapeutic options are urgently required....

W Leconet, C Larbouret, T Chardès, G Thomas, M Neiveyans, M Busson, M Jarlier… in Oncogene (2014)

Article

Reconstitution of regulatory T-cell subsets after allogeneic hematopoietic SCT

Previous studies on regulatory T-cell (Treg) reconstitution after allogeneic hematopoietic SCT (HSCT) have suggested that, within the GVHD process, imbalance between effector T cells and Tregs may be more impo...

A Xhaard, H Moins-Teisserenc, M Busson, M Robin, P Ribaud… in Bone Marrow Transplantation (2014)

Article

A low thymic function is associated with leukemia relapse in children given T-cell-depleted HLA-haploidentical stem cell transplantation

E Clave, D Lisini, C Douay, G Giorgiani, M Busson, M Zecca, D Charron… in Leukemia (2012)

Article

Activating KIR genes are associated with CMV reactivation and survival after non-T-cell depleted HLA-identical sibling bone marrow transplantation for malignant disorders

Combinations of HLA and killer immunoglobulin-like receptors (KIR) may affect outcome in T-cell depleted haematopoietic stem cell transplantation (HSCT). The KIR gene family includes inhibitory (KIR2DL and 3DL...

C Chen, M Busson, V Rocha, M-L Appert, V Lepage, N Dulphy… in Bone Marrow Transplantation (2006)

Article

ERα and ERβ expression and transcriptional activity are differentially regulated by HDAC inhibitors

The proliferative action of ERα largely accounts for the carcinogenic activity of estrogens. By contrast, recent data show that ERβ displays tumor-suppressor properties, thus supporting the interest to identify c...

V Duong, A Licznar, R Margueron, N Boulle, M Busson, M Lacroix… in Oncogene (2006)

Article

Loss of the NPM1 gene in myeloid disorders with chromosome 5 rearrangements

The assignment with chromosome banding techniques of the breakpoints of the recurrent translocation t(3;5) which leads to NPM1/MLF1 gene fusion in myeloid malignancies has not been unequivocal. In order to assess...

R Berger, M Busson, L Baranger, C Hélias, M Lessard, N Dastugue, F Speleman in Leukemia (2006)

Article

NUP214-ABL1 amplification in t(5;14)/HOX11L2-positive ALL present with several forms and may have a prognostic significance

P Ballerini, M Busson, S Fasola, J van den Akker, H Lapillonne, S P Romana… in Leukemia (2005)

Article

Expression of the MN1–TEL fusion protein in the human UCSD/AML1 leukemic cell line

V Della Valle, L Guglielmi, M Busson, E C Zwarthoff, R Berger, O A Bernard in Leukemia (2004)

Article

t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH)

To accurately estimate the incidence of HOX11L2 expression, and determine the associated cytogenetic features, in T-cell acute lymphoblastic leukemia (T-ALL), the Groupe Français de Cytogénétique Hématologique...

R Berger, N Dastugue, M Busson, J van den Akker, C Pérot, P Ballerini… in Leukemia (2003)

Article

DPB1 disparities contribute to severe GVHD and reduced patient survival after unrelated donor bone marrow transplantation

In order to evaluate the impact of HLA-DBP1 incompatibilities on the occurrence of acute graft-versus-host disease (GVHD) in unrelated hematopoietic cell transplantation, we studied 57 donor/recipient pairs ch...

P Loiseau, H Espérou, M Busson, R Sghiri, R Tamouza… in Bone Marrow Transplantation (2002)

Article

Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus

Pemphigus foliaceus (PF) is a rare and severe cutaneous autoimmune disease caused by autoantibodies directed against desmoglein 1 (DSG1), a desmosomal adhesion glycoprotein. We previously showed that the DSG1 ...

P Martel, D Gilbert, M Busson, P Loiseau, V Lepage, L Drouot… in Genes & Immunity (2002)

Article

Identification of functional domains involved in BTG1 cell localization

We have previously shown that BTG1 stimulates myoblast differentiation. In addition, this protein displays a major nuclear localization in confluent myoblasts, decreasing during the early steps of differentiat...

A Rodier, P Rochard, C Berthet, J P Rouault, F Casas, L Daury, M Busson… in Oncogene (2001)

Chapter

The Follow up of the French Grafts

From 1985 to 1994, the 103 french transplantation teams have operated 19910 grafts. We present the follow up of these organs from the data base of France Transplant which is an exhaustive registry of grafted p...

Philippe Romano, M. Busson, J. Hors in Organ Shortage: The Solutions (1995)

Article

A retrospective and prospective study of the number of kidney transplants in 31 countries

The aim of the present study was to try to predict the number of cadaveric kidney transplantations (CKT) that will be performed in the year 1993. The raw data regarding the number of renal transplants that hav...

C. Chevalier, J. M. Dupuy, M. Busson, J. Hors, G. Foulon in Transplant International (1989)

Article

Multiple drug combinations with “low-dose” cyclosporin for renal transplantation

The factors affecting graft survival in transplant recipients receiving cyclosporin (CsA) are still being debated. Our report is based on an analysis of 202 successive transplantations performed in our institu...

C. Hiesse, P. Prevost, M. Busson, O. Lantz, M. Cantarovich… in Transplant International (1988)

Chapter and Conference Paper

HLA and Familial Malignant Melanoma

The aim of this work was to study a possible linkage between susceptibility to familial malignant melanoma (FMM) and the HLA region by geno- ty** multiplex-case families.

J. Hors, F. Demenais, J. P. Cesarini, O. Verola… in Histocompatibility Testing 1984 (1984)

Chapter and Conference Paper

Antigen Report: HLA-Cw7

The antigen Cw7 was first defined by Dehay et al. as CVE. They reported (a) that it was an allele of the HLA-C series; (b) that it was independent of HLA-A and B antigens in cap** experiments; (c) that gene ...

V. Lepage, W. R. Mayr, M. Busson, L. Degos in Histocompatibility Testing 1984 (1984)