7 Result(s)
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Article
Maturation of Calcium Transport in Cardiac Sarcoplasmic Reticulum
ABSTRACT: Developmental changes in myocardial function have been described by a number of investigators. To further define the cellular basis for these changes, the present study was designed to characterize a...
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Article
SEPARATION OF CARDIAC SARCOPLASMIC RETICULUM FROM FETAL AND MATERNAL SHEEP INTO FREE AND JUNCTIONAL SUBPOPULATIONS
We have previously shown decreased Ca accumulation in crude cardiac sarcoplasmic reticulum (SR) vesicles isolated from fetal sheep. However, recent data indicate that the cardiac SR is subspecialized and that ...
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Article
117 INCREASED CALCIUM CHANNEL DENSITY IN CARDIAC SARCOPLASMIC RETICULUM FROM FETAL SHEEP
Decreased active Ca accumulation by vesicles of cardiac sarcoplasmic reticulum (SR) from fetal sheep can in part be attributed to decreased density of Ca pumps. To determine if differences in Ca release channe...
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Article
DECREASED CONTRACTILITY OF THE DUCTUS ARTERIOSUS IN EXPERIMENTAL PULMONIC STENOSIS
Delayed closure of the ductus arteriosus (DA) after birth has been observed in newborn infants with critical pulmonic stenosis (PS) and in lambs with experimental PS. This delayed closure may be the result of ...
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Article
INDOMETHACIN THERAPY ON THE FIRST DAY OF LIFE IN VERY-LOW-BIRTHWEIGHT INFANTS
It has recently been suggested that early treatment with indomethacin(indo) of premature infants with asymptomatic heart murmurs decreased morbidity since the majority of these infants develop hemodynamically ...
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Article
INCREASED CALCIUM PUMP TURNOVER RATE IN CARDIAC SARCOPLASMIC RETICULUM IN FETAL SHEEP
We have previously reported decreased Ca uptake and Ca-dependent ATP hydrolysis in cardiac sarcoplasmic reticulum (SR) vesicles isolated from fetal sheep as compared to SR vesicles from maternal sheep. These i...
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Article
270 EXOGENOUS ARACHIDONIC ACID IS NOT CONVERTED TO PROSTAGLANDIN E2 BY THE LAMB DUCTUS ARTERIOSUS
Prostaglandin (PG) E2 regulates the patency of the ductus arteriosus (DA) in the fetus and preterm neonate. Numerous investigators have used exogenous arachidonic acid (aa), a precursor of PG synthesis, to study ...
