Allergy Matters
New Approaches to Allergy Prevention and Management
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11 Result(s)
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Luud J. W. J. Gilissen
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Gene Editing of Wheat to Reduce Coeliac Disease Epitopes in Gluten
By using gene editing technologies such as CRISPR/Cas, precise modifications can be made in the genome. CRISPR/Cas is especially valuable for targeted mutagenesis in polyploids, as it can induce mutations of m...
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Low Gluten and Coeliac-Safe Wheat Through Gene Editing
Cereal consumption by humans is older than agriculture. During preceding eras, humans gradually acquired the necessary knowledge and tools for processing and cultivation of cereals, making themselves unconscio...
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Allergen Protein Families and Cross-Reactivity
Allergies are defined as an excessive reaction of the immune system to normally harmless proteins. What makes a protein an allergen, and why are some individuals affected but not others? This review deals with...
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Multidisciplinary Approaches to Allergy Prevention
Allergies are a complex medical and societal phenomenon. Its prevention requires well-elaborated actions. The classical avoidance rule is: no allergen, no allergy. However, with the high number of allergenic s...
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In Search of Hypoallergenic Birch Trees: Characterization of PR-10 Genes from Eight Betula Species and Detection of Bet v 1 Isoforms in Birch Pollen Using a Combined Genomics- Proteomics Approach
Bet v 1 is an important cause of hay fever in the northern hemisphere. Bet v 1 isoforms from the European white birch (Betula pendula) have been investigated extensively, but the allergenic potency of other birch...
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Differential transcript abundance and genotypic variation of four putative allergen-encoding gene families in melting peach
We analysed the temporal and spatial transcript expression of the panel of 18 putative isoallergens from four gene families (Pru p 1–4) in the peach fruit, anther and leaf of two melting cultivars, to gain insigh...
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Open AccessPhylogenetic relationships in Betula (Betulaceae) based on AFLP markers
The genus Betula comprises various species in boreal and temperate climate zones of the Northern Hemisphere. The taxonomy of Betula is controversial and complicated by parallel evolution of morphological traits, ...
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Book
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Future developments in allergy prevention: a matter of integrating medical, natural and social sciences
Allergy is a multifactorial disease and has a significant impact on society. Strategies for allergy prevention require integrated and multidisciplinary approaches. A knowledge framework has been designed for t...
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Production of hypoallergenic plant foods by selection, breeding and genetic modification
A set of plant-breeding technologies on the reduction of the allergenicity of food, i.c. the production of hypoallergenic apple cultivars by selection, breeding and genetic modification, is elaborated. The res...
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Article
Regulation and exploitation of genetically modified crops
Functional foods, nutraceuticals and plant-derived medicines may improve public relations for transgenic crop technology, but could leave manufacturers with tricky business decisions to make.
