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Article
Open AccessWithin-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives ...
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Article
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
Multiple methods have been developed to estimate narrow-sense heritability, h2, using single nucleotide polymorphisms (SNPs) in unrelated individuals. However, a comprehensive evaluation of these methods has not ...
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Article
Using partitioned heritability methods to explore genetic architecture
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Article
Population genomics of Populus trichocarpa identifies signatures of selection and adaptive trait associations
Stephen DiFazio and colleagues report the genome sequences and population genomic analyses of 544 black cottonwood trees (Populus trichocarpa) along the Northwest coast of North America. They find evidence for cl...