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Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits

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  1. Article

    Open Access

    Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects

    Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives ...

    Laurence J. Howe, Michel G. Nivard, Tim T. Morris, Ailin F. Hansen in Nature Genetics (2022)

  2. Article

    Using partitioned heritability methods to explore genetic architecture

    Luke M. Evans, Matthew C. Keller in Nature Reviews Genetics (2018)