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Article
Open AccessIdentification of an oncological clinical pathway through questionnaires to health professionals
Clinical Pathways in Oncology can benefit patients using organized interventions to standardize and increase care efficiency. Healthcare systems should have tools to identify their oncological clinical pathway...
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Article
In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions
Thermal therapy has gained popularity over the years, and Portugal is one of the richest European countries in mineral therapeutic waters. The interest in the use of these natural mineral waters (NMW) for derm...
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Article
Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens
The common therapeutic indications of Portuguese Natural Mineral Waters (NMWs) are primarily for respiratory, rheumatic and musculoskeletal systems. However, these NMWs have been increasingly sought for dermat...
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Article
The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis
Nuclear factor E2-related factor 2 (NRF2) is a transcription factor that plays a major role in the regulation of intracellular antioxidant response. The effect of NRF2 overexpression in many malignancies is st...
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Article
Prognosis of hormone-dependent breast cancer seems to be influenced by KEAP1, NRF2 and GSTM1 genetic polymorphisms
Influence of Glutathione S-transferase Mu1 (GSTM1) has long been studied in breast cancer and GSTM1 null genotype was correlated with breast cancer risk. Nuclear factor-erythroid 2-related factor-2 (NRF2) is a tr...
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Article
Open AccessEducational interventions to improve prescription and dispensing of antibiotics: a systematic review
Excessive and inappropriate antibiotic use contributes to growing antibiotic resistance, an important public-health problem. Strategies must be developed to improve antibiotic-prescribing. Our purpose is to re...
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Article
Attitudes of community pharmacists to antibiotic dispensing and microbial resistance: a qualitative study in Portugal
Background The inappropriate use of antibiotics is considered a main cause of microbial resistance. This is an important public health problem. Community pharmacists have an important role in the...
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Article
Genetic Inheritance Effects on Endurance and Muscle Strength
Top-level sport seems to play a natural Darwinian stage. The most outstanding athletes appear to emerge as a result of exogenous influences of nature and/or coincidence, namely, the contingency of practicing c...
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Article
Glutathione S-transferase M1, T1, and P1 genotypes and breast cancer risk: a study in a Portuguese population
Glutathione S-transferases are a superfamily of multifunctional enzymes that play a key role in Phase II metabolism, detoxifying therapeutic drugs, and various carcinogens by conjugation with glutathione. We unde...
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Article
Association between ACE D allele and elite short distance swimming
The influence of ACE gene on athletic performance has been widely explored, and most of the published data refers to an I/D polymorphism leading to the presence (I allele) or absence (D allele) of a 287-bp seq...
