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  1. No Access

    Article

    Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

    It is increasingly evident that genes known to perform critical roles during early embryogenesis, particularly during stem cell renewal, pluripotentiality and survival, are also expressed during the developmen...

    Luigi Strizzi, Caterina Bianco, Nicola Normanno, David Salomon in Oncogene (2005)

  2. No Access

    Article

    Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-β signaling

    We present evidence that Notch4ICD attenuates TGF-β signaling. Cells expressing the activated form of the Notch4 receptor (ICD4) were resistant to the growth-inhibitory effects of TGF-β. Notch4ICD was found to bi...

    You** Sun, William Lowther, Katsuaki Kato, Caterina Bianco, Nicholas Kenney… in Oncogene (2005)

  3. No Access

    Article

    Human Cripto-1 overexpression in the mouse mammary gland results in the development of hyperplasia and adenocarcinoma

    Human Cripto-1 (CR-1) is overexpressed in approximately 80% of human breast, colon and lung carcinomas. Mouse Cr-1 upregulation is also observed in a number of transgenic (Tg) mouse mammary tumors. To determin...

    Christian Wechselberger, Luigi Strizzi, Nicholas Kenney, Morihisa Hirota… in Oncogene (2005)