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Article

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation

There are significant commonalities among several pathologies involving fibroblasts, ranging from auto-immune diseases to fibrosis and cancer. Early steps in cancer development and progression are closely link...

Luigi Mazzeo, Soumitra Ghosh, Emery Di Cicco, Jovan Isma… in Nature Communications (2024)