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    Article

    Baohuoside I inhibits FXR signaling pathway to interfere with bile acid homeostasis via targeting ER α degradation

    Epimedii folium (EF) is an effective herbal medicine in osteoporosis treatment, but the clinical utilization of EF has been limited due to potential hepatotoxicity. The previous studies identified that baohuos...

    Zhen Zhao, Lu-Lu Yang, Qiao-Lei Wang, **-Fa Du… in Cell Biology and Toxicology (2023)

  2. Article

    Open Access

    E3 ubiquitin ligase RNF5 attenuates pathological cardiac hypertrophy through STING

    Ring-finger protein 5 (RNF5) is an E3 ubiquitin ligase which is expressed in a variety of human tissues. RNF5 is involved in the regulation of endoplasmic reticulum stress, inflammation, and innate immunity an...

    Lu-Lu Yang, Wen-Chang **ao, Huan Li, Zheng-Yang Hao, Gui-Zhi Liu… in Cell Death & Disease (2022)

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