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Article
Baohuoside I inhibits FXR signaling pathway to interfere with bile acid homeostasis via targeting ER α degradation
Epimedii folium (EF) is an effective herbal medicine in osteoporosis treatment, but the clinical utilization of EF has been limited due to potential hepatotoxicity. The previous studies identified that baohuos...
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Article
Open AccessE3 ubiquitin ligase RNF5 attenuates pathological cardiac hypertrophy through STING
Ring-finger protein 5 (RNF5) is an E3 ubiquitin ligase which is expressed in a variety of human tissues. RNF5 is involved in the regulation of endoplasmic reticulum stress, inflammation, and innate immunity an...
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Article
Porous β-FeOOH nanotube stabilizing Au single atom for high-efficiency nitrogen fixation
Electrochemical nitrogen reduction reaction (NRR) under ambient conditions is highly desirable to achieve sustainable ammonia (NH3) production via an alternative carbon free strategy. Single-atom catalysts (SACs)...
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Article
The Evolution of Quantum Discord and Entanglement in the XXZ Heisenberg Spin Chain under Ornstein-Uhlenbeck Noise
The dynamics of entanglement measured by concurrence and quantum correlation described by quantum discord under Ornstein-Uhlenbeck noise are investigated in several different cases. Our study mainly found that...
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Article
Open AccessA multicenter survey of first-line treatment patterns and gene aberration test status of patients with unresectable Stage IIIB/IV nonsquamous non-small cell lung cancer in China (CTONG 1506)
In recent years, systemic chemotherapy and molecular targeted therapy have become standard first-line treatments for locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). The objective...
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Article
Increased expression of IL-28RA mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune and inflammatory disease with a strong genetic contribution and characterized by kinds of immune reactions. Our previous genome-wide association stud...
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Article
Open AccessAssociation analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Currently, numerous genetic loci of SLE have been confirmed. Here we try to further explore additional genes contributing to SLE suscepti...
