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  1. No Access

    Article

    Water-Soluble Se-Containing Proteins from Chicken Alleviate DSS-Induced Ulcerative Colitis in Mice via Inhibiting TLR4/MyD88 Pathway and Protecting the Goblet Cell Pathway

    The influence of water-soluble selenium-containing proteins (WSSeP) in chicken on ulcerative colitis (UC) is not known. This work aims to investigate the effect of two WSSeP including h-Se with 1.78 μg Se/g an...

    Yuancheng Li, Yanlong Xu, **n Hu, Chenxi Li, Lulu Wei… in Biological Trace Element Research (2024)

  2. No Access

    Article

    The Relationship Between Heavy Metals and Missed Abortion: Using Mediation of Serum Hormones

    Accumulating evidence suggests that heavy metal exposure may have adverse effects on the fetal development. Furthermore, disruption of serum hormone homeostasis can result in the adverse pregnancy outcomes. Th...

    Haixia Liu, Zhilan Li, Li’ao **e, Guangzhuang **g… in Biological Trace Element Research (2024)

  3. No Access

    Article

    Combination of Selenite and Butyrate Enhances Efficacy Against Colon Cancer by Targeting ASCT2-Mediated Amino Acid Metabolism

    Drug combination is considered to be an effective approach to improve the efficacy of cancer therapy and chemoprevention. Selenite, a representative of inorganic form of selenium, and butyrate, a major short-c...

    **ling Cui, **gsi Li, Shuang Zhao, Lihong Fan… in Biological Trace Element Research (2024)

  4. No Access

    Article

    miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN

    Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (PH) which is a life-threatening complication of acute pulmonary embolism (APE). This st...

    Lei Tang, Shuai Niu, **wei Xu, Wei Lu, Li Zhou in Cytotechnology (2024)

  5. No Access

    Article

    The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction

    Aluminum (Al) is a low toxic trace element that can accumulate in the nervous system and induce cognitive disorders characterized by reduced learning and memory ability. Neuroepigenetic effects are structural ...

    Jie Gao, Wei Liu, **g Pei, **g Li, Ni** Hao… in Biological Trace Element Research (2024)

  6. No Access

    Article

    Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China

    Exposure to essential and toxic metals occurs simultaneously as a mixture in real-life. However, there is no consensus regarding the effects of co-exposure to multiple metal(loid)s (designated hereafter metals...

    Guihua Du, **aoguang Song, Fankun Zhou, Lu Ouyang… in Biological Trace Element Research (2024)

  7. No Access

    Article

    Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study

    Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...

    Chen Li, **angwen Peng, Jiayang Zheng, Kexin Shi… in Biological Trace Element Research (2024)

  8. No Access

    Article

    The modification of heme special importer to improve the production of active hemoglobins in Escherichia coli

    To enhance the import of heme for the production of active hemoproteins in Escherichia coli C41 (DE3) lacking the special heme import system, heme receptor ChuA from E. coli Nissle 1917 was modified through molec...

    Zihan Zhang, Baodong Hu, Tao Zhang, Zhengshan Luo, **gwen Zhou… in Biotechnology Letters (2024)

  9. No Access

    Article

    Effects of miR-204-5p and Target Gene EphB2 on Cognitive Impairment Induced by Aluminum Exposure in Rats

    Aluminum is a common environmental neurotoxin. Aluminum ions can cross the blood–brain barrier and accumulate in different brain regions, damage brain tissue, and cause cognitive impairment, but the molecular ...

    Wei Liu, Jie Gao, Ni** Hao, **g Li, **g Pei… in Biological Trace Element Research (2024)

  10. No Access

    Article

    Metabolic engineering of Saccharomyces cerevisiae for high-level production of (+)-ambrein from glucose

    (+)-Ambrein is the primary component of ambergris, a rare product found in sperm whales (Physeter microcephalus). Microbial production using sustainable resources is a promising way to replace animal extraction a...

    Chumin Lin, **aopeng Zhang, Zhongju Ji, Baolian Fan, Yaman Chen… in Biotechnology Letters (2024)

  11. No Access

    Article

    Regulation of oxidative stress response and antioxidant modification in Corynebacterium glutamicum

    As an efficient and safe industrial bacterium, Corynebacterium glutamicum has extensive application in amino acid production. However, it often faces oxidative stress induced by reactive oxygen species (ROS), lea...

    Yueshu Li, Yuanyi Guo, Fangyuan Niu, Hui Gao… in World Journal of Microbiology and Biotechn… (2024)

  12. Article

    Open Access

    Targeting oncogene-induced cellular plasticity for tumor therapy

    Cellular plasticity, the remarkable adaptability of cancer cells to survive under various stress conditions, is a fundamental hallmark that significantly contributes to treatment resistance, tumor metastasis, ...

    Bin Li, Lingling Zheng, Jianhua Yang, Lianghu Qu in Advanced Biotechnology (2024)

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  13. No Access

    Article

    Fluorescence Recognition of Hydrazine Driven by Neighboring Group Participation

    Hydrazine (N2H4) has toxic effects on the environment. Although a variety of reactive probes have been used to identify hydrazine, practical applications required continuous development of hydrazine fluorescent p...

    Wenzhi Xu, Xue Li, Shuo Wang, Honglei Zhang, Wei Li in Journal of Fluorescence (2024)

  14. No Access

    Article

    Quantitative trait locus analysis of gray leaf spot resistance in the maize IBM Syn10 DH population

    The exploration and dissection of a set of QTLs and candidate genes for gray leaf spot disease resistance using two fully assembled parental genomes may help expedite maize resistance breeding.

    Lina Cui, Mingfei Sun, Lin Zhang, Hongjie Zhu… in Theoretical and Applied Genetics (2024)

  15. No Access

    Article

    Antibody MYH9 and Antibiotic Lidamycin Inhibit the Growth and Proliferation of Lung Cancer Cells and Induce Their Apoptosis

    The aim of this study was to investigate the impact of the antibiotic lidamycin (LDM) and the targeted therapy with the antibody Myosin heavy chain 9 (MYH9) on cancer cells, aiming to provide insights for canc...

    Jie Jiang, Ruoyu Hu, Zhuoshuan Li, Wei He in Molecular Biotechnology (2024)

  16. No Access

    Article

    Effects of Commonly used Surfactants, Poloxamer 188 and Tween 80, on the Drug Transport Capacity of Intestinal Glucose Transporters

    Some glycoside drugs can be transported through intestinal glucose transporters (IGTs). The surfactants used in oral drug preparations can affect the function of transporter proteins. This study aimed to inves...

    Jiasheng Chen, Zhenzhen Chen, Wentao Wang, Liyang Wang, Jiaqi Zheng… in AAPS PharmSciTech (2024)

  17. No Access

    Article

    Blockade of PD-1 and TIM-3 Ameliorates CD8+ T Cell Exhaustion in a Mouse Model of Chronic Myeloid Leukemia

    The immune system plays a pivotal role in controlling chronic myeloid leukemia (CML). CD8+ T cell exhaustion results in reduced effectiveness of T cell-mediated immunity, thereby contributing to disease progressi...

    Ting **, Fei Gao, Li Wang in Cell Biochemistry and Biophysics (2024)

  18. No Access

    Article

    Research Progress of ARTP Mutagenesis Technology Based on Citespace Visualization Analysis

    Atmospheric and room temperature plasma (ARTP) mutagenesis technology has been developed rapidly in recent years because of its simple operation, safety, environmental friendliness, high mutation rate, and lar...

    Shun Gao, Li Li, Yonggong Wei, Lei Wen, Shujuan Shao… in Molecular Biotechnology (2024)

  19. No Access

    Article

    Suppressing the virulence factors of Candida auris with baicalein through multifaceted mechanisms

    Candida auris, a rapidly spreading multi-drug‐resistant fungus, is causing lethal infections under certain conditions globally. Baicalin (BE), an active ingredient extracted from the dried root of Scutellaria bai...

    Can Li, Jun Wang, Hao Li, Yemei Wang, Hui Wu, Wenfan Wei… in Archives of Microbiology (2024)

  20. No Access

    Article

    Norwogonin aids in fighting MRSA-induced pneumonia by targeting agrAC to inhibit α-hemolysin production

    The increasing prevalence of infections related to methicillin-resistant Staphylococcus aureus (MRSA) necessitates the exploration of innovative therapeutic strategies that diverge from conventional antibiotic tr...

    Chang Liu, Juan Hou, **nran Ren, Xuerui Guo… in World Journal of Microbiology and Biotechn… (2024)

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