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11 Result(s)
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Lu**g Li
Engineering
Human Genetics
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Living Reference Work Entry In depth
Bioinspired Fabrication of Peptide-Based Capsid-Like Nanoparticles for Gene Delivery
Biomimetic nanomaterials have shown great potentials for improving therapeutic delivery. This chapter describes a novel macromolecular and supramolecular strategy to drive the assembly of peptide dendrimers an...
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Living Reference Work Entry In depth
Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA
Small interfering RNA (siRNA) showed promising prospect in the fields of basic research and drug development due to its capability in inhibition of the expression of any interest gene. However, delivery is the...
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Book
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Chapter
Evaluation of the Reliability of cDNA Microarray Technique
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Chapter
Fast Screening of Single-Nucleotide Polymorphisms Using Chip-Based Temperature Gradient Capillary Electrophoresis
Recently, the analysis of single-nucleotide polymorphisms has attracted much attention. Although many techniques have been reported, new methods with high resolving power, low-cost and fast speed are still in ...
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Chapter
Photoactivatable Silanes: Synthesis and Uses in Biopolymer Array Fabrication on Glass Substrates
We wish to report a fast and easy way to build hydrophobic layers and hydrophilic functional polymer layers thereafter onto glass surfaces. A benzophenone-based silane was synthesized and used to prepare stabl...
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Chapter
An Integrated Biochemoinformatics System for Drug Discovery
Chipscreen Biosciences, Ltd. (www.chipscreen.com) is a drug discovery company specialized in novel small molecule therapeutics. Chipscreen has developed a proprietary chemical genomics approach to accelerate t...
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Chapter
Electronic Biosensors Based on DNA Self-Assembled Monolayer on Gold Electrodes
Information concerning the immobilization and hybridization of DNA on a surface is paramount to the development of DNA-based electronic biosensors. This study looks at recent investigations of DNA immobilized ...
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Chapter
Improvement of Microarray Technologies for Detecting Single Nucleotide Mismatch
With the completion of the Human Genome Project and beginning of post genome era, there is an urgent need for a fast, specific, sensitive, reliable and cost-effective method for the genome-wide polymorphism an...
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Chapter
Comparison of CsI(Ti) and Scintillating Plastic in a Multi-Pinhole/CCD-Based Gamma Camera for Small-Animal Low-Energy SPECT
SPECT with submillimeter resolution (µSPECT)is needed for small-animal imaging and differs from clinical SPECT a rich and well-established methodology of nuclear medicine in that its focus is on the specific r...
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Chapter
A Multidetector High-Resolution SPECT/CT Scanner with Continuous Scanning Capability
Small animal imaging has become an important tool in research of human biology and disease. These techniques include high-resolution ultrasound, computed tomography (CT), positron emission tomography (PET), an...
