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Article
Open AccessAcute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention
Exercise exerts many health benefits by directly inducing molecular alterations in physically utilized skeletal muscle. Molecular adaptations of subcutaneous adipose tissue (SCAT) might also contribute to the ...
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Article
Open AccessSex differences in central insulin action: Effect of intranasal insulin on neural food cue reactivity in adults with normal weight and overweight
Central insulin action influences cognitive processes, peripheral metabolism, and eating behavior. However, the contribution of obesity and sex on central insulin-mediated neural food cue processing still rema...
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Article
Langzeiteffekte von Diabetespräventionsmaßnahmen
Diabetesprävention kann durch Lebensstilintervention, Pharmakotherapie oder eine Kombination aus beiden erreicht werden. In einer Vielzahl von wegweisenden randomisierten, kontrollierten Studien wurde festgest...
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Article
Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes prevention: results from the TULIP study
Lifestyle intervention is effective to prevent type 2 diabetes. However, a considerable long-term non-response occurs to a standard lifestyle intervention. We investigated which risk phenotypes at baseline and...
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Article
Erratum to: A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation
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Article
A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation
Insulin resistance underlies the etiology of both type 2 diabetes and gestational diabetes. In pregnancy, insulin resistance is also associated with an unfavorable metabolic programming of the fetus, potential...
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Article
Maternal insulin sensitivity is associated with oral glucose-induced changes in fetal brain activity
Fetal programming plays an important role in the pathogenesis of type 2 diabetes. The aim of the present study was to investigate whether maternal metabolic changes during OGTT influence fetal brain activity.