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    Article

    Deep domain adversarial neural network for the deconvolution of cell type mixtures in tissue proteome profiling

    Cell type deconvolution is a computational method for the determination/resolution of cell type proportions from bulk sequencing data, and is frequently used for the analysis of divergent cell types in tumour ...

    Fang Wang, Fan Yang, Longkai Huang, Wei Li, Jiangning Song in Nature Machine Intelligence (2023)

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    Open Access

    USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer

    Colorectal cancer (CRC) is one of the most common digestive malignant tumors in the world. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis, and abnormal expression of Snail1 is...

    Fakun Huang, Chengying Zheng, Longkai Huang, Changqing Lin in Cancer Cell International (2020)