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  1. Article

    Open Access

    Aptamer functionalized nucleic acid nano drug for targeted synergistic therapy for colon cancer

    Due to its complicated pathophysiology, propensity for metastasis, and poor prognosis, colon cancer is challenging to treat and must be managed with a combination of therapy. Using rolling circle transcription...

    Liye Zhu, Jieyu Yuhan, Hao Yu, Boyang Zhang, Longjiao Zhu in Journal of Nanobiotechnology (2023)

  2. No Access

    Article

    Sandwich capture ultrasensitive sensor based on biohybrid interface for the detection of Cronobacter sakazakii

    A simple, rapid and ultrasensitive visual sensing method for the detection of Cronobacter sakazakii (C. sakazakii) based on a biohybrid interface was established. During the entire sensing process, quadruple-casc...

    **uyuan Xu, Longjiao Zhu, **nxin Wang, **nyue Lan in Applied Microbiology and Biotechnology (2022)

  3. No Access

    Article

    Fluorescent detection of Cu (II) ions based on DNAzymatic cascaded cyclic amplification

    A fluorescent biosensor based on the cascaded cyclic amplification-lighted copper nanoparticles has been developed, optimized, and validated. In the double-modular cascaded cyclic amplification, a DNAzymatic c...

    **g**g Tian, Zaihui Du, Longjiao Zhu, **angli Shao, **angyang Li in Microchimica Acta (2020)

  4. No Access

    Article

    A colorimetric zinc(II) assay based on the use of hairpin DNAzyme recycling and a hemin/G-quadruplex lighted DNA nanoladder

    A method is described for sensitive colorimetric determination of zinc(II) ions that uses (a) a Zn(II)-responsive hairpin DNAzyme that assists target recycling, (b) hybridization chain reaction, and (c) hemin/...

    Longjiao Zhu, Guishan Li, **angli Shao, Kunlun Huang, Yunbo Luo in Microchimica Acta (2019)

  5. No Access

    Article

    Colorimetric detection and ty** of E. coli lipopolysaccharides based on a dual aptamer-functionalized gold nanoparticle probe

    A rapid method for identification and ty** of lipopolysaccharides (LPS) was developed by utilizing the different binding affinities between two kinds of gold nanoparticles (AuNPs) functionalized with two apt...

    Longjiao Zhu, Shuting Li, **angli Shao, Yuxiang Feng, Peiyan **e in Microchimica Acta (2019)

  6. Article

    Open Access

    A rapid and visual turn-off sensor for detecting copper (II) ion based on DNAzyme coupled with HCR-based HRP concatemers

    To solve the requirement of on-site, rapid, and visual detection of copper (II) (Cu2+) in aqueous solution, a turn-off sensor for detecting copper (II) ion was developed based on Cu2+-dependent DNAzyme as the rec...

    Wentao Xu, **g**g Tian, Yunbo Luo, Longjiao Zhu, Kunlun Huang in Scientific Reports (2017)

  7. Article

    Open Access

    Highly sensitive detection of lipopolysaccharides using an aptasensor based on hybridization chain reaction

    Lipopolysaccharides (LPS), integral components of the outer membrane of all gram-negative bacteria, are closely associated with foodborne diseases such as fever, diarrhea and hypotension and thus, the early an...

    Peiyan **e, Longjiao Zhu, **angli Shao, Kunlun Huang, **g**g Tian in Scientific Reports (2016)

  8. Article

    Open Access

    Development of a double-antibody sandwich ELISA for rapid detection of Bacillus Cereus in food

    Bacillus cereus is increasingly recognized as one of the major causes of food poisoning in the industrialized world. In this paper, we describe a sensitive double-antibody sandwich enzyme-linked immunosorbent ass...

    Longjiao Zhu, **g He, **aohan Cao, Kunlun Huang, Yunbo Luo in Scientific Reports (2016)