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  1. Article

    Open Access

    Clinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review

    The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pat...

    Peng Zhang, Baoyi Liu, Shuang Zhang, Xuefei Chang, Lihe Zhang, Dejian Gu in Critical Care (2024)

  2. No Access

    Article

    STED Imaging of Vesicular Endocytosis in the Synapse

    Endocytosis is a fundamental biological process that couples exocytosis to maintain the homeostasis of the plasma membrane and sustained neurotransmission. Super-resolution microscopy enables optical imaging o...

    Shaoqin Hu, Zhenli **e, Bianbian Wang, Yang Chen, Zexin **g in Neuroscience Bulletin (2024)

  3. No Access

    Article

    Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling

    Dopaminergic neurons play a crucial role in associative learning, but their capacity to regulate behavior on subsecond timescales remains debated. It is thought that dopaminergic neurons drive certain behavior...

    Charltien Long, Kwang Lee, Long Yang, Theresia Dafalias in Nature Neuroscience (2024)

  4. No Access

    Article

    Copper-catalyzed enantioselective desymmetrizing C(sp2)–H functionalization of azide-ynamides via α-imino copper carbenes

    α-Imino metal carbenes are versatile intermediates in organic synthesis, and have broad applications in the assembly of divergent N-heterocycles. However, the catalytic enantioselective desymmetrization based on

    En-He Huang, Li-Gao Liu, You-Wei Yin, Hao-Xuan Dong, Ji-Jia Zhou in Science China Chemistry (2024)

  5. No Access

    Article

    Recent advances and perspectives in MXene-based cathodes for aqueous zinc-ion batteries

    Aqueous zinc-ion batteries (AZIBs) show great potential for applications in grid-scale energy storage, given their intrinsic safety, cost effectiveness, environmental friendliness, and impressive electrochemic...

    Aiduo Wu, Tianhao Wang, Long Zhang in International Journal of Minerals, Metallu… (2024)

  6. No Access

    Article

    ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway

    Refractory wounds are a severe complication of diabetes mellitus that often leads to amputation because of the lack of effective treatments and therapeutic targets. The pathogenesis of refractory wounds is com...

    Tianru Huyan, Lu Fan, Zhong-yuan Zheng, **g-hui Zhao in Acta Pharmacologica Sinica (2024)

  7. No Access

    Article

    High-mobility group box 1 and its related receptors: potential therapeutic targets for contrast-induced acute kidney injury

    Percutaneous coronary intervention (PCI) is a crucial diagnostic and therapeutic approach for coronary heart disease. Contrast agents’ exposure during PCI is associated with a risk of contrast-induced acute ki...

    Changhua Mo, Qili Huang, Lixia Li, Yusheng Long in International Urology and Nephrology (2024)

  8. Article

    Open Access

    Measurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector

    Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...

    G. Aad, E. Aakvaag, B. Abbott, S. Abdelhameed, K. Abeling in Journal of High Energy Physics (2024)

  9. Article

    Open Access

    Search for central exclusive production of top quark pairs in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with tagged protons

    A search for the central exclusive production of top quark-antiquark pairs ( t t ...

    A. Tumasyan, W. Adam, J. W. Andrejkovic, T. Bergauer in Journal of High Energy Physics (2024)

  10. Article

    Open Access

    Search for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV

    A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...

    A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic in Journal of High Energy Physics (2024)

  11. No Access

    Article

    3D-printed self-healing, biodegradable materials and their applications

    3D printing is a versatile technology capable of rapidly fabricating intricate geometric structures and enhancing the performance of flexible devices in comparison to conventional fabrication methods. However,...

    Yu Li, Guangmeng Ma, Fawei Guo, Chunyi Luo, Han Wu in Frontiers of Mechanical Engineering (2024)

  12. Article

    Open Access

    Brain effect mechanism of lever positioning manipulation on LDH analgesia based on multimodal MRI: a study protocol

    The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Lever Positioning Manipulation (LPM), which is closely linked to the brain's pain-regulating mechanisms. Magnetic Re...

    **ng-chen Zhou, Long-hao Chen, Shuang Wu in BMC Complementary Medicine and Therapies (2024)

  13. Article

    Open Access

    Neuroendoscopic Parafascicular Evacuation of Spontaneous Intracerebral Hemorrhage (NESICH Technique): A Multicenter Technical Experience with Preliminary Findings

    Intracerebral hemorrhage (ICH) is a severe manifestation of stroke, demonstrating notably elevated global mortality and morbidity. Thus far, effective therapeutic strategies for ICH have proven elusive. Curren...

    Long Wang, **aodong Li, Zhongyong Deng, Qiang Cai, Pan Lei, Hui Xu in Neurology and Therapy (2024)

  14. No Access

    Article

    Terpyridine-based metallo-cuboctahedron nanomaterials for efficient photocatalytic degradation of persistent organic pollutants

    Metal–organic cage photocatalysts with nanoscale dimensions have received wide attention in the field of photocatalytic environmental pollutant treatment due to their large cavities, easy modification, high tu...

    Qixia Bai, Yan Huang, Zhihong Chen, Yilin Pan, **aohan Zhang, Qingwu Long in Nano Research (2024)

  15. No Access

    Article

    Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner

    Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...

    Bian-lei Yang, Yao-ying Long, Qian Lei, Fei Gao in Acta Pharmacologica Sinica (2024)

  16. Article

    Open Access

    Cloud inversion analysis of surrounding rock parameters for underground powerhouse based on PSO-BP optimized neural network and web technology

    Aiming at the shortcomings of the BP neural network in practical applications, such as easy to fall into local extremum and slow convergence speed, we optimized the initial weights and thresholds of the BP neu...

    Long Qu, Hong-Qiang **e, Jian-Liang Pei, You-Gen Li, Jia-Ming Wu in Scientific Reports (2024)

  17. Article

    Open Access

    A phase 3 randomised double-blind placebo-controlled trial of mirtazapine as a pharmacotherapy for methamphetamine use disorder: a study protocol for the Tina Trial

    There are no approved pharmacotherapies for methamphetamine use disorder. Two preliminary phase 2 randomised controlled trials have found mirtazapine, a tetracyclic antidepressant, to be effective in reducing ...

    Rebecca McKetin, Tayla J. Degan, Lucy Saunders, Long Nguyen, Gregory Dore in Trials (2024)

  18. No Access

    Article

    Paternal obesity induces subfertility in male offspring by modulating the oxidative stress-related transcriptional network

    The effects of fathers’ high-fat diet (HFD) on the reproductive health of their male offspring (HFD- F1) remain to be elucidated. Parental obesity is known to have a negative effect on offspring fertility, but...

    Long Li, Yuxuan Ma, Chao Zhu, Yan Li, Heran Cao in International Journal of Obesity (2024)

  19. Article

    Open Access

    Search for heavy neutral leptons in final states with electrons, muons, and hadronically decaying tau leptons in proton-proton collisions at \( \sqrt{s} \) = 13 TeV

    A search for heavy neutral leptons (HNLs) of Majorana or Dirac type using proton-proton collision data at ...

    A. A. Hayrapetyan, A. Tumasyan, W. Adam in Journal of High Energy Physics (2024)

  20. Article

    Open Access

    Amplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay

    The resonant structure of the radiative decay Λ b 0 ...

    R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta in Journal of High Energy Physics (2024)

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