3,184 Result(s)
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Open AccessClinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review
The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pat...
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STED Imaging of Vesicular Endocytosis in the Synapse
Endocytosis is a fundamental biological process that couples exocytosis to maintain the homeostasis of the plasma membrane and sustained neurotransmission. Super-resolution microscopy enables optical imaging o...
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Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling
Dopaminergic neurons play a crucial role in associative learning, but their capacity to regulate behavior on subsecond timescales remains debated. It is thought that dopaminergic neurons drive certain behavior...
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Copper-catalyzed enantioselective desymmetrizing C(sp2)–H functionalization of azide-ynamides via α-imino copper carbenes
α-Imino metal carbenes are versatile intermediates in organic synthesis, and have broad applications in the assembly of divergent N-heterocycles. However, the catalytic enantioselective desymmetrization based on
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Recent advances and perspectives in MXene-based cathodes for aqueous zinc-ion batteries
Aqueous zinc-ion batteries (AZIBs) show great potential for applications in grid-scale energy storage, given their intrinsic safety, cost effectiveness, environmental friendliness, and impressive electrochemic...
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ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway
Refractory wounds are a severe complication of diabetes mellitus that often leads to amputation because of the lack of effective treatments and therapeutic targets. The pathogenesis of refractory wounds is com...
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High-mobility group box 1 and its related receptors: potential therapeutic targets for contrast-induced acute kidney injury
Percutaneous coronary intervention (PCI) is a crucial diagnostic and therapeutic approach for coronary heart disease. Contrast agents’ exposure during PCI is associated with a risk of contrast-induced acute ki...
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Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Open AccessSearch for central exclusive production of top quark pairs in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with tagged protons
A search for the central exclusive production of top quark-antiquark pairs ( t t ...
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Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
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3D-printed self-healing, biodegradable materials and their applications
3D printing is a versatile technology capable of rapidly fabricating intricate geometric structures and enhancing the performance of flexible devices in comparison to conventional fabrication methods. However,...
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Open AccessBrain effect mechanism of lever positioning manipulation on LDH analgesia based on multimodal MRI: a study protocol
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Lever Positioning Manipulation (LPM), which is closely linked to the brain's pain-regulating mechanisms. Magnetic Re...
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Open AccessNeuroendoscopic Parafascicular Evacuation of Spontaneous Intracerebral Hemorrhage (NESICH Technique): A Multicenter Technical Experience with Preliminary Findings
Intracerebral hemorrhage (ICH) is a severe manifestation of stroke, demonstrating notably elevated global mortality and morbidity. Thus far, effective therapeutic strategies for ICH have proven elusive. Curren...
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Terpyridine-based metallo-cuboctahedron nanomaterials for efficient photocatalytic degradation of persistent organic pollutants
Metal–organic cage photocatalysts with nanoscale dimensions have received wide attention in the field of photocatalytic environmental pollutant treatment due to their large cavities, easy modification, high tu...
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Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Open AccessCloud inversion analysis of surrounding rock parameters for underground powerhouse based on PSO-BP optimized neural network and web technology
Aiming at the shortcomings of the BP neural network in practical applications, such as easy to fall into local extremum and slow convergence speed, we optimized the initial weights and thresholds of the BP neu...
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Open AccessA phase 3 randomised double-blind placebo-controlled trial of mirtazapine as a pharmacotherapy for methamphetamine use disorder: a study protocol for the Tina Trial
There are no approved pharmacotherapies for methamphetamine use disorder. Two preliminary phase 2 randomised controlled trials have found mirtazapine, a tetracyclic antidepressant, to be effective in reducing ...
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Paternal obesity induces subfertility in male offspring by modulating the oxidative stress-related transcriptional network
The effects of fathers’ high-fat diet (HFD) on the reproductive health of their male offspring (HFD- F1) remain to be elucidated. Parental obesity is known to have a negative effect on offspring fertility, but...
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Open AccessSearch for heavy neutral leptons in final states with electrons, muons, and hadronically decaying tau leptons in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for heavy neutral leptons (HNLs) of Majorana or Dirac type using proton-proton collision data at ...
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Open AccessAmplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay
The resonant structure of the radiative decay Λ b 0 ...