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Article
Nicotinamide Mononucleotide Improves Spermatogenic Disorders in Aluminum-Exposed Rats by Modulating the Glycolytic Pathway
This study aimed to investigate the protective effect of nicotinamide mononucleotide (NMN) on testicular spermatogenesis in aluminum chloride (AlCl3)-exposed rats and to elucidate the potential underlying mechani...
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Article
Fine map** of powdery mildew resistance gene MlWE74 derived from wild emmer wheat (Triticum turgidum ssp. dicoccoides) in an NBS-LRR gene cluster
Powdery mildew resistance gene MlWE74, originated from wild emmer wheat accession G-748-M, was mapped in an NBS-LRR gene cluster of chromosome 2BS.
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Article
Open AccessDNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells
ADAMTS9 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family, and its expression is frequently silenced due to promoter hypermethylation in various human cancer...
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Article
Open AccessRNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells
Ring finger protein 180 (RNF180) is an important member of the E3 ubiquitin ligase family. As a tumor suppressor gene, RNF180 is significantly associated with the prognosis of patients with gastric cancer (GC)...
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Article
Effects of Groundwater Level Changes Associated with Coastline Changes in Coastal Wetlands
Coastline changes caused by anthropogenic and natural influences inevitably alter coastal wetland groundwater levels. In this study, we apply Visual MODFLOW (VMOD) to assess the influence of different zonal co...
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Article
Hatchery technology restores the spawning ground of phytophilic fish in the urban river of Yangtze Estuary, China
Due to the concrete slope protection projects conducted around urban rivers in many megalopolises, increased attention has been paid to fish biodiversity losses accompanying urban development. Hatchery technol...
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Article
River damming affects energy flow and food web structure: a case study from a subtropical large river
The river discontinuity caused by damming can modify both the availability of production sources and the energy flow in riverine food webs. We hypothesized the carbon source support food web would vary among t...
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Article
Nutritional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase at the enzymatic and molecular levels in cobia Rachycentron canadum
Despite being a carnivorous fish species, cobia (Rachycentron canadum) can utilize high levels of dietary carbohydrate (up to 360 g kg−1). By contrast, rainbow trout (also carnivorous) cannot, due to the absence ...
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Article
Molecular identification of dmrt1 and its promoter CpG methylation in correlation with gene expression during gonad development in Culter alburnus
Dmrt1, a member of the Dmrt family, is an important transcription regulator of gender determination. To study the biological function of dmrt1 in sexual differentiation and its potential implication in breeding t...
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Article
Effects of replacing fish meal with rubber seed meal on growth, nutrient utilization, and cholesterol metabolism of tilapia (Oreochromis niloticus × O. aureus)
A feeding trial was conducted to evaluate the effects of replacing fish meal with rubber seed meal (RSM) on growth, nutrient utilization, and cholesterol metabolism of tilapia (Oreochromis niloticus × Oreochromis...
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Article
Effect of annexin A7 suppression on the apoptosis of gastric cancer cells
Understanding the molecular mechanism of gastric cancer cell apoptosis is pivotal for the development of precise therapies targeting this disease. In the present study, we examined the effects of annexin A7 in...
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Article
Two isoforms of hormone-sensitive lipase b are generated by alternative exons usage and transcriptional regulation by insulin in grass carp (Ctenopharyngodon idella)
The aim of this study was to investigate the gene structure of two hormone-sensitive lipase b (HSLb) isoforms and their transcriptional regulation by insulin in grass carp (Ctenopharyngodon idella). HSL is an imp...
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Article
Molecular cloning of glucose transporter 1 in grouper Epinephelus coioides and effects of an acute hyperglycemia stress on its expression and glucose tolerance
The glucose transporter family proteins play pivotal roles in glucose metabolism. In this study, we successfully cloned the orange spotted grouper (Epinephelus coioides) glucose transporter 1 (EcGlut1) gene (GenB...
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Article
Dietary silymarin supplementation promotes growth performance and improves lipid metabolism and health status in grass carp (Ctenopharyngodon idellus) fed diets with elevated lipid levels
This study was carried out to evaluate whether silymarin supplementation influences growth, lipid metabolism, and health status in grass carp fed elevated dietary lipid levels. The juvenile fish (27.43 ± 0.17 ...
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Article
Effect of Reducing Nitric Oxide in Rumex K-1 Leaves on the Photoprotection of Photosystem II Under High Temperature with Strong Light
The purpose of this study was to explore the effect of reducing nitric oxide (NO) in Rumex K-1 leaves on the photoprotection of photosystem II (PSII) under high temperature with strong light. Reducing the conten...
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Article
Novonestmycins A and B, two new 32-membered bioactive macrolides from Streptomyces phytohabitans HBERC-20821
Two new 32-membered macrolide compounds, named Novonestmycins A (1) and B (2), were isolated from the soil strain Streptomyces phytohabitans HBERC-20821. Their structures were elucidated by using spectroscopic me...
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Article
Overexpression of PTP1B in human colorectal cancer and its association with tumor progression and prognosis
Protein tyrosine phosphatase 1B (PTP1B) is a non-transmembrane protein tyrosine phosphatase that has been implicated in cancer pathogenesis. However, the expression level and the role of PTP1B in the developme...
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Article
Fitness benefits and costs of induced defenses in Daphnia carinata (Cladocera: Daphnidae) exposed to cyanobacteria
Induced defenses can shape the trophic interactions between prey and predators, but the presence, benefits, and costs of induced defenses against harmful algae in zooplankton are little known. Here, the hypoth...
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Article
Structure and seasonal dynamics of bacterial communities in three urban rivers in China
Although a large number of recent ecological studies have focused on freshwater bacterioplankton populations, knowledge of the primary factors influencing bacterial communities in urban rivers is limited. Bact...
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Article
MnHSP90 cDNA characterization and its expression during the ovary development in oriental river prawn, Macrobrachium nipponense
Heat shock protein 90 (HSP90) is not only involved in environmental stress but also plays roles in the ovary development in some vertebrates. To understand its role in crustacean, we examined the HSP90 cDNA for t...