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    Article

    Identification of region-specific amino acid signatures for doxorubicin-induced chemo brain

    Doxorubicin (DOX) is a cornerstone of chemotherapy for solid tumors and leukemias. DOX-induced cognitive impairment, termed chemo brain, has been reported in cancer survivors, whereas its mechanism remains poo...

    Peijia Liu, Linling Guo, **nyue Yu, Peipei Liu, Yan Yu, **aotong Kong in Amino Acids (2023)

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    Metabolic network-based identification of plasma markers for non-small cell lung cancer

    Metabolic markers, offering sensitive information on biological dysfunction, play important roles in diagnosing and treating cancers. However, the discovery of effective markers is limited by the lack of well-...

    Linling Guo, Linrui Li, Zhiyun Xu, Fanchen Meng in Analytical and Bioanalytical Chemistry (2021)

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    Article

    Attenuation of doxorubicin-induced oxidative damage in rat brain by regulating amino acid homeostasis with Astragali Radix

    The nervous system disorders caused by doxorubicin (DOX) are among the severe adverse effects that dramatically reduce the quality of life of cancer survivors. Astragali Radix (AR), a popular herbal drug and d...

    **nyue Yu, Linling Guo, **aoying Deng, Fang Yang, Yuan Tian, Peifang Liu in Amino Acids (2021)